Quantitative assessment of portal hypertension with bi-parametric dual-frequency hepatic MR elastography in mouse models

J Li, TS Sehrawat, J Chen, MB Hilscher, KJ Glaser… - European …, 2021 - Springer
Liver stiffness measured by transient elastography (TE) has also shown significant
correlations with portal pressure in both preclinical and clinical studies [32]. It strongly …

… , sleep duration and smoking status with elastographic parameters of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements

I Mikolasevic, V Domislovic… - … journal of clinical …, 2021 - Wiley Online Library
… the blockade of transforming growth factor β expression and of its downstream inductor
connective tissue growth factor. Third, caffeine can inhibit hepatic stellate cells and subsequently …

[HTML][HTML] The non-invasive assessment of hepatic fibrosis

G Gheorghe, S Bungău, G Ceobanu, M Ilie… - Journal of the Formosan …, 2021 - Elsevier
… There is a strong relationship between liver fibrosis and … , HGF – hepatocyte growth factor)
and cytokines that inhibit … MRE has proven its superiority to transient elastography through the …

Serum proteomic profiling of patients with compensated advanced chronic liver disease with and without clinically significant portal hypertension

F Pastrovic, R Novak, I Grgurevic, S Hrkac, G Salai… - Plos one, 2024 - journals.plos.org
… is elastography, especially transient elastography (TE) in … of the proliferation of connective
tissue in the liver would be overly … order to search for growth factors and cytokines with known …

Stiffness and hepatocytes function in vitro

S Kidambi - Liver Elastography: Clinical Use and Interpretation, 2020 - Springer
… Clinical research assessing liver stiffness by transientliver-enriched transcription factors,
including hepatocyte nuclear … stiffness and potential relationship among substrate stiffness, …

High throughput interrogation of human liver stellate cells reveals microenvironmental regulation of phenotype

A Brougham-Cook, I Jain, DA Kukla, F Masood… - Acta biomaterialia, 2022 - Elsevier
… were diluted in a 2x growth factor buffer solution comprised of … Given this relationship,
measuring collagen I expression is a … correlate with one another as a function of ECM and …

Association of adipokines with hepatic steatosis and fibrosis in chronic hepatitis B patients on long‐term nucleoside analogue

LY Mak, CH Lee, KS Cheung, DKH Wong… - Liver …, 2019 - Wiley Online Library
… (NA) with accurate transient elastography measurement, we … causal relationship between
adipokines and CHB-related liver … and protein expression of connective tissue growth factor,50 …

[HTML][HTML] Vitamin D and liver fibrosis: Molecular mechanisms and clinical studies

W Udomsinprasert, J Jittikoon - Biomedicine & pharmacotherapy, 2019 - Elsevier
… protein including connective tissue growth factor (CTGF) during … were negatively correlated
with the degree of liver fibrosis, … also associated with liver stiffness in transient elastography. …

A two-dimensional (2d) systems biology-based discrete liver tissue model: A simulation study with implications for ultrasound elastography of liver fibrosis

Y Wang, J Jiang - Computers in biology and medicine, 2019 - Elsevier
… For each model, one transient cycle of plane shear or … correlation length (CL) were calculated
from all microscopic … Table 4 summarizes the liver stiffness values of four METAVIR stages …

In Situ Regulation and Mechanisms of 3D Matrix Stiffness on the Activation and Reversion of Hepatic Stellate Cells

G Chen, Y Deng, B Xia, Y Lv - Advanced Healthcare Materials, 2023 - Wiley Online Library
… ) by using transient elastography to detect the liver stiffness of … that liver stiffness is significantly
positively correlated with the … pro-fibrotic factors such as transforming growth factor-beta 1 (…