CD133‐Src‐TAZ signaling stimulates ductal fibrosis following DDC diet‐induced liver injury

HT Oh, W Heo, GD Yoo, KM Kim… - Journal of Cellular …, 2022 - Wiley Online Library
… fibrosis inducers, including connective tissue growth factor (Ctgf)… Transient transfection of
HCT116 cells was performed using … These results suggest a functional correlation between TAZ …

Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis

A Filliol, Y Saito, A Nair, DH Dapito, LX Yu… - Nature, 2022 - nature.com
… relevance, the causal relationship between fibrosis and HCC … -enriched mediator and that
hepatic growth factor (HGF) was … reduced tumour number and liver stiffness when Col1a1 was …

[HTML][HTML] Microfibrillar-associated protein 4 in health and disease

R Kanaan, M Medlej-Hashim, R Jounblat, B Pilecki… - Matrix Biology, 2022 - Elsevier
… fiber macromolecules of connective tissue. In vertebrates, … tissues, microfibrils play an
important role in modulating the bioavailability of growth factors such as transforming growth factor

[HTML][HTML] The role of matrix stiffness in cancer stromal cell fate and targeting therapeutic strategies

J Wei, J Yao, M Yan, Y Xie, P Liu, Y Mao, X Li - Acta biomaterialia, 2022 - Elsevier
connective tissue growth factor … A superfamily of transient receptor potential (TRP) ion
channels on the cell … Increased matrix stiffness is inversely correlated with the expression of …

Fibrosis in liver and pancreas: A review on pathogenic significance, diagnostic options, and current management strategies

T Dasgupta, V Manickam - Inflammation, 2023 - Springer
growth factors (PDGF) come under the class of dimeric isoforms which acts on connective
tissue … is transient elastography which works on the principle of the velocity of the wave and …

Progressive reduction in skeletal muscle mass to visceral fat area ratio is associated with a worsening of the hepatic conditions of non-alcoholic fatty liver disease

T Shida, N Oshida, S Oh, K Okada… - … , metabolic syndrome and …, 2019 - Taylor & Francis
… , transient elastography showed higher levels of liver stiffness (… fat mass measured by BIA
is highly correlated with the … ), a member of the transforming growth factor β family, is a potent …

Insulin resistance/sensitivity measures as screening indicators of metabolic-associated fatty liver disease and liver fibrosis

ME Khamseh, M Malek, S Jahangiri, S Nobarani… - Digestive Diseases and …, 2024 - Springer
Transient elastography was used to estimate liver stiffness and controlled attenuation …
connective tissue growth factor [55,56,57]. Also, Cai et al. demonstrated a significant correlation

Fibrosis in chronic liver disease: an update on diagnostic and treatment modalities

P Manka, A Zeller, WK Syn - Drugs, 2019 - Springer
… for tissue development), transforming growth factor (TGF)-β (the … to quantify the amount of
connective tissue on Masson’s … Transient elastography assesses liver fibrosis by measuring the …

[HTML][HTML] Identification of drivers of breast cancer invasion by secretome analysis: insight into CTGF signaling

JW Hellinger, F Schömel, JV Buse, C Lenz… - Scientific Reports, 2020 - nature.com
… includes expression of connective tissue growth factor (CTGF) … normal breast tissue, no
recognizable correlations between … (D) 3 D spheroid assay was performed after transient CTGF …

[HTML][HTML] Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans

K Pafili, M Roden - Molecular Metabolism, 2021 - Elsevier
… TAG content (assessed using magnetic resonance spectroscopy, … agents including fibroblast
growth factor agonists (FGF21a), … was shown to correlate with the severity of liver fibrosis but …