Engineered skeletal muscles for disease modeling and drug discovery
… disease to accurately predict drug efficacy and toxicity in humans has prompted the development
in vitro models of human skeletal muscle that fatefully recapitulate cell and tissue level …
in vitro models of human skeletal muscle that fatefully recapitulate cell and tissue level …
Predictors for fibrosis regression in chronic HCV patients after the treatment with DAAS: results of a real-world cohort study
… or more) evident by transient elastography (TE) examination … To analyze the relationship
between pretreatment possible … cytokines such as transforming growth factor 1 β, hyaluronic acid…
between pretreatment possible … cytokines such as transforming growth factor 1 β, hyaluronic acid…
Perlecan in pericellular mechanosensory cell-matrix communication, extracellular matrix stabilisation and mechanoregulation of load-bearing connective tissues
… to changes in osmolarity with transient changes in intracellular Ca 2… proteins and growth
factors, eg, transforming growth factor-β (TGF-β… Correlation of the type VI collagen and perlecan …
factors, eg, transforming growth factor-β (TGF-β… Correlation of the type VI collagen and perlecan …
[HTML][HTML] Mechanical feed-forward loops contribute to idiopathic pulmonary fibrosis
MAT Freeberg, A Perelas, JK Rebman… - The American Journal of …, 2021 - Elsevier
… , Piezo channels, transient receptor potential channels, and … forces within tissues activate
latent transforming growth factor-β (… Tissue stiffness, measured in kilopascals (kPa), measures …
latent transforming growth factor-β (… Tissue stiffness, measured in kilopascals (kPa), measures …
Liver stiffness, hepatorenal index, and microRNA-130b as predictors for chronic kidney disease in patients with non-alcoholic fatty liver disease
MYE Hassafy, AS Elhadidi, MM Tahoon… - Egyptian Liver …, 2023 - Springer
… A comparison between proportions was determined by the chi-… In the current study, a positive
correlation was found … fat accumulation through insulin-like growth factor binding protein 2 (…
correlation was found … fat accumulation through insulin-like growth factor binding protein 2 (…
Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues
… Hepatic macrophages, essential to maintain tissue homeostasis and ensure rapid responses
to hepatic injury, include Kupffer cells (KC, liver … accumulate in the injured liver. These cells, …
to hepatic injury, include Kupffer cells (KC, liver … accumulate in the injured liver. These cells, …
Prevalence and Crucial Parameters in Diabesity-Related Liver Fibrosis: A Preliminary Study
S Suwała, A Białczyk, K Koperska, A Rajewska… - Journal of Clinical …, 2023 - mdpi.com
… by an objective and validated method of transient … diabesity, the correlation between liver
stiffness index and GGTP … -fused long-acting fibroblast growth factor 21 (FGF21) analogue as a …
stiffness index and GGTP … -fused long-acting fibroblast growth factor 21 (FGF21) analogue as a …
The role of fibrosis and liver-associated fibroblasts in the pathogenesis of hepatocellular carcinoma
J Baglieri, DA Brenner, T Kisseleva - International journal of molecular …, 2019 - mdpi.com
… fibrosis, positively correlate with HCC risk [23,24,25]. … by several cytokines and growth factors,
which are secreted by … -shaped cells of the connective tissues that produce collagen. Later …
which are secreted by … -shaped cells of the connective tissues that produce collagen. Later …
NAFLD is associated with quiescent rather than active Crohn's disease
… Transient elastography and liver biopsy were requested by … transforming growth factor β
concentration measured enzyme-… the absence of correlation between severity of liver fat (PDFF) …
concentration measured enzyme-… the absence of correlation between severity of liver fat (PDFF) …
Hexokinase 2 couples glycolysis with the profibrotic actions of TGF-β
X Yin, M Choudhury, JH Kang, KJ Schaefbauer… - Science …, 2019 - science.org
… muscle actin, and connective tissue growth factor) and stabilized … Therefore, we further
assessed the relationship between … (A) AKR-2B cells were transiently transfected with a YAP/TAZ …
assessed the relationship between … (A) AKR-2B cells were transiently transfected with a YAP/TAZ …