[HTML][HTML] Connectivity of the corticostriatal and thalamostriatal systems in normal and parkinsonian states: an update
AC Martel, A Galvan - Neurobiology of disease, 2022 - Elsevier
… of diverse cortical inputs onto the striatal interneurons and SPNs… IT and PT cortical neurons
project to both projection neurons … by side glutamatergic inputs to GABAergic interneurons. In …
project to both projection neurons … by side glutamatergic inputs to GABAergic interneurons. In …
What Is the Role of the Intralaminar Thalamic Input to the Striatum and Its Potential Implications in Parkinson Disease?
E Benarroch - Neurology, 2023 - AAN Enterprises
… presynaptic suppression of cortical input to both direct and … but ultimately contributes to the
imbalance between the indirect (… contribute to movement initiation and rescued parkinsonian …
imbalance between the indirect (… contribute to movement initiation and rescued parkinsonian …
Contribution of cholinergic interneurons to striatal pathophysiology in Parkinson's disease
S Ztaou, M Amalric - Neurochemistry international, 2019 - Elsevier
… dopaminergic neurons innervating the striatum, the main input … from MSNs and GABAergic
interneurons during in vivo … striatal DA-ACh balance and thus, treat parkinsonian symptoms. …
interneurons during in vivo … striatal DA-ACh balance and thus, treat parkinsonian symptoms. …
Cholinergic interneurons amplify thalamostriatal excitation of striatal indirect pathway neurons in Parkinson's disease models
A Tanimura, Y Du, J Kondapalli, DL Wokosin… - Neuron, 2019 - cell.com
… populations of GABAergic spiny projection neurons (SPNs) … addition to that from the cerebral
cortex. This thalamostriatal … Our results show that, in the parkinsonian state, an imbalance …
cortex. This thalamostriatal … Our results show that, in the parkinsonian state, an imbalance …
What's wrong with the striatal cholinergic interneurons in Parkinson's disease? Focus on intrinsic excitability
C Tubert, MG Murer - European Journal of Neuroscience, 2021 - Wiley Online Library
… ChIs activity ameliorates parkinsonian symptoms and modifies L-… that thalamic input is
stronger than cortical input in ChIs and … nicotinic receptors in GABAergic interneurons (Figure 2c). …
stronger than cortical input in ChIs and … nicotinic receptors in GABAergic interneurons (Figure 2c). …
[HTML][HTML] Striatal synaptic adaptations in Parkinson's disease
… from an imbalance in the excitability of striatal efferent projection … input to the striatum comes
from the cerebral cortex, the … in restoring running in mice that were parkinsonian. Thus, while …
from the cerebral cortex, the … in restoring running in mice that were parkinsonian. Thus, while …
Cellular and synaptic dysfunctions in Parkinson's disease: stepping out of the striatum
N Mallet, L Delgado, M Chazalon, C Miguelez… - Cells, 2019 - mdpi.com
… entry structure of the BG and the principal recipient of cortical … This GABAergic nucleus
consists of 95% projection neurons, … an imbalance in activity in striatal projection neurons that …
consists of 95% projection neurons, … an imbalance in activity in striatal projection neurons that …
Dopaminergic modulation of striatal function and Parkinson's disease
… signaling is not limited to imbalance in the average spiking in … easily observed in iSPNs of
parkinsonian animals, there has … CB1R is abundant in cortical neurons but barely detectable …
parkinsonian animals, there has … CB1R is abundant in cortical neurons but barely detectable …
Changing views of the pathophysiology of Parkinsonism
T Wichmann - Movement Disorders, 2019 - Wiley Online Library
… of striatal dopamine in the parkinsonian state increases striatal … an imbalance between the
(antikinetic) actions of striatal … affect cortical inputs to the striatum,209 thalamostriatal inputs …
(antikinetic) actions of striatal … affect cortical inputs to the striatum,209 thalamostriatal inputs …
Synaptic determinants of cholinergic interneurons hyperactivity during parkinsonism
M Padilla-Orozco, M Duhne… - Frontiers in Synaptic …, 2022 - frontiersin.org
… , not expressed in striatal projection neurons. Therefore, … inhibitory synaptic inputs onto CINs
during the Parkinsonian state … that excitatory glutamatergic inputs from cortex and thalamus …
during the Parkinsonian state … that excitatory glutamatergic inputs from cortex and thalamus …