Dual role of YY1 in HPV life cycle and cervical cancer development

A Warowicka, J Broniarczyk, M Węglewska… - International journal of …, 2022 - mdpi.com
… types often leads to the integration of the HPV genome into the … The repressive capacity of
YY1 is controlled by the central … be deacetylated by HDAC deacetylases, while the acetylation

Yin Yang 1 is a potent activator of human T lymphotropic virus type 1 LTR-driven gene expression via RNA binding

GZ Wang, SP Goff - … of the National Academy of Sciences, 2020 - National Acad Sciences
… retroviruses, results in the establishment of an integrated proviral copy of the viral genome,
chromatin modifiers such as histone methyltransferase SETDB1, histone deacetylases, and …

[PDF][PDF] Epigenetic Mechanisms of HIV-1 Persistence. Vaccines 2021, 9, 514

R Verdikt, O Hernalsteens, C Van Lint - 2021 - pdfs.semanticscholar.org
… -1 DNA and before its integration in the host chromatin [43]. In … in coordinating nucleosome
occupancy, possibly through … regarding histone acetylation, seemingly opposite histone

Histone chaperone CAF‐1 promotes HIV‐1 latency by leading the formation of phase‐separated suppressive nuclear bodies

X Ma, T Chen, Z Peng, Z Wang, J Liu, T Yang… - The EMBO …, 2021 - embopress.org
Chromatin “eraser” modifiers, such as histone deacetylases … higher when supplemented
with histone deacetylase (HDAC) … not transcribed from a few of integrated HIV‐1, we quantified …

[PDF][PDF] Balance between Retroviral Latency and Transcription: Based on HIV Model. Pathogens 2021, 10, 16

A Pluta, JP Jaworski, CN Cortés-Rubio - 2020 - pdfs.semanticscholar.org
… transcription of integrated DNA from 5 … histone deacetylase-dependent manner. In contrast,
when it is bound to T3, T3Rα leads to chromatin remodeling, including histone acetylation

ZBTB gene expression in HIV patients: a possible new molecular mechanism of viral control

JC De Arcos-Jiménez, LA González-Hernández… - Archives of …, 2021 - Springer
… Once integrated, the proviral DNA is replicated along with the … part of a complex containing
histone deacetylases (HDAC3), … cells that maintain the production capacity of the cytokines IL-…

[图书][B] Using a CRISPR-based screen to study individual and combination molecular mechanisms of HIV-1 latency

E Hsieh - 2022 - search.proquest.com
… the process of expansion of cells with an integrated HIVY1 … associated with deacetylation
of the histones at the LTR [124]. … histone tail and BrD4 occupancy on the HIVY1 LTr, and the …

Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a Cure

NN Duggan, T Dragic, SK Chanda, L Pache - Viruses, 2023 - mdpi.com
… 69%) of integration sites being in active genes or in regional … Histone acetylation relaxes
euchromatin, rendering … reduces the genome-wide chromatin occupancy of PAF1C and thereby …

Genetic and epigenetic regulation of natural resistance to HIV-1 infection: new approaches to unveil the HESN secret

C Fenizia, I Saulle, M Clerici… - Expert Review of Clinical …, 2020 - Taylor & Francis
… The integration of such information will provide important … is chromatin modification, such as
acetylation/deacetylation … STAT1, NF-kB/p65 and histone deacetylase (HDAC)-2 recruited at …

HIV-1 Transcription Inhibition Using Small RNA-Binding Molecules

P Khatkar, G Mensah, S Ning, M Cowen, Y Kim… - Pharmaceuticals, 2023 - mdpi.com
… the transcription of the integrated proviral genome. Therefore, … maintain nucleosomes in a
deacetylated state, which results … Moving forward, we also examined the occupancy of Src-1 in …