[HTML][HTML] Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a Cure
… 69%) of integration sites being in active genes or in regional … Histone acetylation relaxes
euchromatin, rendering … reduces the genome-wide chromatin occupancy of PAF1C and thereby …
euchromatin, rendering … reduces the genome-wide chromatin occupancy of PAF1C and thereby …
[HTML][HTML] HIV-1 Transcription Inhibition Using Small RNA-Binding Molecules
… the transcription of the integrated proviral genome. Therefore, … maintain nucleosomes in a
deacetylated state, which results … Moving forward, we also examined the occupancy of Src-1 in …
deacetylated state, which results … Moving forward, we also examined the occupancy of Src-1 in …
[HTML][HTML] Resveratrol decreases the expression of genes involved in inflammation through transcriptional regulation
DML Pinheiro, AHS de Oliveira, LG Coutinho… - Free Radical Biology …, 2019 - Elsevier
… protein acetylation, we also evaluated histone methylation … revealed Friend leukemia
integration 1 transcription factor (… and compromises the regenerative capacity of hematopoietic …
integration 1 transcription factor (… and compromises the regenerative capacity of hematopoietic …
A multiple sclerosis–protective coding variant reveals an essential role for HDAC7 in regulatory T cells
… This effect is counterregulated by protein phosphatase 2A (… assay to measure T reg capacity
to suppress the proliferation of … orchestrate chromatin remodeling, they can also deacetylate …
to suppress the proliferation of … orchestrate chromatin remodeling, they can also deacetylate …
[HTML][HTML] The transcriptional corepressor CBFA2T3 inhibits all-trans-retinoic acid–induced myeloid gene expression and differentiation in acute myeloid leukemia
N Steinauer, C Guo, J Zhang - Journal of Biological Chemistry, 2020 - ASBMB
… We also show that CBFA2T3 function is linked to decreased chromatin accessibility at RARα
target genes via regulation of HAT recruitment and histone acetylation, independent of the …
target genes via regulation of HAT recruitment and histone acetylation, independent of the …
[HTML][HTML] Postmortem Brains from Subjects with Diabetes mellitus display reduced GLUT4 expression and soma area in hippocampal neurons: Potential involvement of …
… increased histone acetylation grade by histone deacetylase 3 (… The integrated density of
stained proteins and determination … in vivo studies, the capacity of metformin to improve GLUT4 …
stained proteins and determination … in vivo studies, the capacity of metformin to improve GLUT4 …
[HTML][HTML] Human transcription factor YY1 could upregulate the HIV-1 gene expression
KL Yu, YM Jung, SH Park, SD Lee, JC You - BMB reports, 2020 - ncbi.nlm.nih.gov
… proteins, is known to function in chromatin remodeling (1). This … acetylation of 155-295
region would decrease the HIV-1 production, we predicted the acetylation site(s) using Acetylation …
region would decrease the HIV-1 production, we predicted the acetylation site(s) using Acetylation …
Clinical Eradication of Latent HIV Reservoirs: Where are we Now?
LM Wong, G Jiang - Frontiers in Clinical Drug Research-HIV …, 2021 - books.google.com
… During quiescence, histone deacetylase is recruited to the HIV LTR and is bound by …
Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated …
Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated …
CBX4 contributes to HIV‐1 latency by forming phase‐separated nuclear bodies and SUMOylating EZH2
L Wu, T Pan, M Zhou, T Chen, S Wu, X Lv, J Liu… - EMBO …, 2022 - embopress.org
… -talk with histone acetylation and corresponding deacetylases. We also conducted chromatin
… The HIV-1 mini-genome was integrated in the intron of human RALGDS gene. Five pairs of …
… The HIV-1 mini-genome was integrated in the intron of human RALGDS gene. Five pairs of …
Endothelial-specific YY1 governs sprouting angiogenesis through directly interacting with RBPJ
Angiogenesis, the formation of new blood vessels, is tightly regulated by gene transcriptional
programs. Yin Ying 1 (YY1) is a ubiquitously distributed transcription factor with diverse …
programs. Yin Ying 1 (YY1) is a ubiquitously distributed transcription factor with diverse …