[HTML][HTML] Alterations of gut microbiota by overnutrition impact gluconeogenic gene expression and insulin signaling
L He - International journal of molecular sciences, 2021 - mdpi.com
… blood glucose levels, counterregulatory mechanisms are activated … The acetylation of histones
by CBP and P300′s … the muscle that exceeds its handling capacity, and excess glucose …
by CBP and P300′s … the muscle that exceeds its handling capacity, and excess glucose …
[HTML][HTML] Diabetic nephropathy: novel molecular mechanisms and therapeutic targets
C Zoja, C Xinaris, D Macconi - Frontiers in Pharmacology, 2020 - frontiersin.org
… ACE2 is an 805 amino-acid type 1 integral membrane … slit pore integrity and renal filtration
capacity–and nestin–a … by histone acetylation/deacetylation, with deacetylated histones …
capacity–and nestin–a … by histone acetylation/deacetylation, with deacetylated histones …
[HTML][HTML] Advances in therapeutic targeting of cancer stem cells within the tumor microenvironment: an updated review
… enhanced DNA damage repair capacity, with phosphorylation of … and deacetylation of histones
are carried out by histone … As a result of the integration of genetic, epigenetic mechanisms …
are carried out by histone … As a result of the integration of genetic, epigenetic mechanisms …
[HTML][HTML] New developments in T cell immunometabolism and implications for cancer immunotherapy
… the mitochondrial spare respiratory capacity (SRC) and … promotes histone acetylation
and chromatin accessibility and … histone deacetylase Sirt1, we observed increased protein …
and chromatin accessibility and … histone deacetylase Sirt1, we observed increased protein …
DAMP-promoted efferent innate immune responses in human diseases: inflammation
WG Land, WG Land - Damage-Associated Molecular Patterns in Human …, 2020 - Springer
… , histone modifications (acetylation and deacetylation, … to take care of providing
counterregulation/counterbalance of biological … are adaptable and can integrate environmental …
counterregulation/counterbalance of biological … are adaptable and can integrate environmental …
[HTML][HTML] YY1 and CP2c in unidirectional spermatogenesis and stemness
… Although chromatin structural modification by Polycomb is essential for gene silencing in …
, RNF51; B cell-specific moloney murine leukemia virus integration site 1, BMI-1), HPH (human …
, RNF51; B cell-specific moloney murine leukemia virus integration site 1, BMI-1), HPH (human …
Spic regulates one-carbon metabolism and histone methylation in ground-state pluripotency
F Mirzadeh Azad, EA Struys, V Wingert, L Hannibal… - Science …, 2023 - science.org
… co-occupancy of NANOG at SPIC binding sites (fig. S1D), we next assessed how SPIC affects
NANOG binding to chromatin. We … This integrative analysis allowed us to focus on five high-…
NANOG binding to chromatin. We … This integrative analysis allowed us to focus on five high-…
The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells
… Tmem cells have strong effector recall capacity and persist without … For example, sgRNAs
against the histone lysine … ), a histone acetyl transferase that facilitates H3/H4 acetylation,33 …
against the histone lysine … ), a histone acetyl transferase that facilitates H3/H4 acetylation,33 …
CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation
… Mitotic kinases are counterregulated by phosphatases such as … significantly diminished
by H2B K5 acetylation. To identify the … We suggest that chromatin association of SET may be …
by H2B K5 acetylation. To identify the … We suggest that chromatin association of SET may be …
[HTML][HTML] The role of macrophages in HIV-1 persistence and pathogenesis
Z Kruize, NA Kootstra - Frontiers in microbiology, 2019 - frontiersin.org
… -integration latency, which is established after integration of the HIV-1 proviral DNA into
the host chromatin, is in contrast to pre-integration … in turn recruits histone deacetylase 1 (HDAC1)…
the host chromatin, is in contrast to pre-integration … in turn recruits histone deacetylase 1 (HDAC1)…