… HDAC1/2-mediated histone deacetylation is known to … Slug occupancy on the Fasn promoter
was assessed by ChIP… modifications confer permissive chromatin conformations on which …

… respiratory capacity (SRC). SRC refers to the reserve energy-generating … Acetate can
enhance histone acetylation and chromatin … The histone deacetylase 6-specific inhibitor (HDAC6i) …

… outgrow O 2 diffusion capacity leading to intratumoral hypoxic … PERK is a known activator
of the integrated stress response (… family of GPCRs and histone deacetylases, such as GPR41 …

… Metabolites are used for histone modifications, eg acetyl-CoA for histone acetylation and
metabolites also regulate activity of chromatin modifying enzymes [111]. PAMPs activate …

… (CBD) that play integral roles in the transcriptional programme of … , engage a counterregulatory
network to determine CD8+ T-… in diminished proliferative capacity of mouse embryonic …

… cell types and their structural integration into the heart. Potential … in the absence of
counterregulatory mechanisms may also … of chromatin structure and the acetylation of histone …

… 9 acetylation 134 (H3K9ac), histone H3 lysine 27 acetylation … We found that chromatin
regions enriched with H3K18la or … , we compared RNApol II occupancy of regions marked by …

… nucleus and integrated into … chromatin hypoacetylation and repressive histone methylation
[99][104][105]. These modifications are made by recruitment of Class I Histone Deacetylases (…

… Loss of actively transcribing chromatin and CLOCK occupancy … = histone deacetylase 1
HDAC2 = histone deacetylase 2 … genome showed the acetylation signature at histone 3 lysines 9 …

… neuroendocrine functions that integrate metabolic information … adult brain, have maintained
their capacity to proliferate in the … rats, histone deacetylase 4 (Hdac4, a class of chromatin …