CpG oligonucleotides as vaccine adjuvants
N Kayraklioglu, B Horuluoglu, DM Klinman - DNA Vaccines: Methods and …, 2021 - Springer
… CpG ODN were effective as vaccine adjuvants in multiple species. CpG ODN adjuvanted
AVA induced a rapid and protective toxin-neutralizing Ab response in guinea pigs [113]. Calves …
AVA induced a rapid and protective toxin-neutralizing Ab response in guinea pigs [113]. Calves …
Vaccine adjuvants: Understanding the structure and mechanism of adjuvanticity
… vaccine adjuvants, including optimization of adjuvant formulations, design of new adjuvants
and … As efficient vaccine adjuvants, CpG ODN can promote the immunostimulatory effect of …
and … As efficient vaccine adjuvants, CpG ODN can promote the immunostimulatory effect of …
Evaluation of immunogenicity and protective efficacy of a CpG-adjuvanted DNA vaccine against Tembusu virus
H Chen, M Yan, Y Tang, Y Diao - Veterinary Immunology and …, 2019 - Elsevier
… a DNA vaccine based on a recombinant pre-membrane (prM) and envelope (E) protein,
using CpG oligodeoxynucleotide (ODN) as an adjuvanted, … , a DNA vaccine pVAX1-prM/E-CpG, …
using CpG oligodeoxynucleotide (ODN) as an adjuvanted, … , a DNA vaccine pVAX1-prM/E-CpG, …
The content of CpG-DNA in antigen-CpG conjugate vaccines determines their cross-presentation activity
RM Clauson, B Berg, B Chertok - Bioconjugate Chemistry, 2019 - ACS Publications
… one CpG per OVA. Our findings suggest that tuning molecular composition of antigen-CpG …
molecular tuning and may be useful for continued development of antigen-CpG vaccines. …
molecular tuning and may be useful for continued development of antigen-CpG vaccines. …
The CpG molecular structure controls the mineralization of calcium phosphate nanoparticles and their immunostimulation efficacy as vaccine adjuvants
R Khalifehzadeh, H Arami - Nanoscale, 2020 - pubs.rsc.org
… While this study is focused to evaluate CaP-CpG nanoparticles as potential adjuvants for
enhanced vaccine delivery applications, we envision that our results will also enable better …
enhanced vaccine delivery applications, we envision that our results will also enable better …
[HTML][HTML] An overview of vaccine adjuvants: current evidence and future perspectives
… It has been shown in a murine model that CpG-B ODN as an adjuvant causes
considerable and long-lasting antibody production, better than alum-adjuvated or non-adjuvated …
considerable and long-lasting antibody production, better than alum-adjuvated or non-adjuvated …
CpG-adjuvanted hepatitis B vaccine (HEPLISAV-B®) update
GH Lee, SG Lim - Expert Review of Vaccines, 2021 - Taylor & Francis
… Expert opinion: HEPLISAV-B, a CpG adjuvant mixed with HBsAg, is more efficacious and
produced earlier seroprotection compared to existing vaccines, with a favorable safety profile. …
produced earlier seroprotection compared to existing vaccines, with a favorable safety profile. …
A CpG-riched plasmid as vaccine adjuvant reduce antigen dose of an inactivated Vibrio anguillarum vaccine in turbot (Scophthalmus maximus L.)
X Sun, P Jin, Q Liu, Q Wang, Y Zhang, X Liu - Fish & shellfish immunology, 2020 - Elsevier
… CpG reduce antigen dose in mice [16] and high dosage may increase product-cost and
workload, we wonder whether CpG ODNs could be used as a safer adjuvant … class B CpG ODNs …
workload, we wonder whether CpG ODNs could be used as a safer adjuvant … class B CpG ODNs …
A DNA nanodevice-based vaccine for cancer immunotherapy
S Liu, Q Jiang, X Zhao, R Zhao, Y Wang, Y Wang… - Nature Materials, 2021 - nature.com
… DNA nanodevice vaccine generated by precisely assembling two types of molecular adjuvants
… CpG motifs (TLR9 agonist) as adjuvant 2 (Supplementary Fig. 4). The sticky ends of the …
… CpG motifs (TLR9 agonist) as adjuvant 2 (Supplementary Fig. 4). The sticky ends of the …
CpG-based nanovaccines for cancer immunotherapy
W Chen, M Jiang, W Yu, Z Xu, X Liu, Q Jia… - International Journal …, 2021 - Taylor & Francis
… On the basis of this technical theory, studies have proposed an innovative research idea,
using CpG DNA not only as the immune adjuvant, but also as the carrier material of …
using CpG DNA not only as the immune adjuvant, but also as the carrier material of …
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