… and correlated with the transfection efficiency. We found that most … to lPEI/DNA NPs, except
for NP2 at PEG grafting density 3% … grafting density and terminal group length are also critical …

… The critical Q 0 above which consistent DLS size for the … The small difference in in vivo delivery
efficiency and … luciferase gene driven by a tumor-specific PEG-3 promoter, as we reported …

… and high transfection efficiency for the regeneration of critical-… of copolymers composed of
methoxy PEG (mPEG) and poly(… hydrodynamic diameter of 25 kDa lPEI/DNA complexes at N/P …

… It was previously observed that the PEG length or grafting density influences the physico-…
with them, both in vitro and in vivo, and thereby also their DNA-binding efficiency. However, the …

… terminal groups and different PEG grafting ratios as mRNA carriers. We examined the effect
of … The intracellular release of mRNA from the NPs is a critical step toward the successful …

… . grafted PEG to polyethyleneimine (PEI) to varying degrees and observed that transfection
was inhibited at lower PEG densities in vivo (IV delivery … The spleen is critical in mediating the …

… /P ratio is critical to the transfection efficiency of polycation/DNA … lPEI/DNA nanoparticles
decorated by DPPC and DMG-PEG have a higher oral gene delivery and transfection efficiency …

… tion, and transfection efficiency, lPEI/DNA polyplexes exhibit … PEG for siRNA delivery were
grafting 10 or 4 molecules PEG … and in vivo delivery of siRNA and quantum dots. Mol. Pharm.…

… is still the issue of in vivo delivery of small RNA molecules (siRNAs)… critically relies on the
grafting with tyrosine. Optimal complex stabilities, which need to be sufficiently high for efficient …

… delivery vehicles with polyethylene glycol (PEG) can improve diffusion through mucus, but
PEG coatings can also inhibit gene delivery. … was the standard in vitro delivery concentration) …