Evaluation of sucrose laurate as an intestinal permeation enhancer for macromolecules: ex vivo and in vivo studies
F McCartney, M Rosa, DJ Brayden - Pharmaceutics, 2019 - mdpi.com
… , isolated rat intestinal tissue mucosae, and rat intestinal … increases in paracellular marker
fluxes and TEER reductions with 5 … [62] also compared C 10 with sucrose caprate in promoting …
fluxes and TEER reductions with 5 … [62] also compared C 10 with sucrose caprate in promoting …
[HTML][HTML] Sodium glycodeoxycholate and sodium deoxycholate as epithelial permeation enhancers: in vitro and ex vivo intestinal and buccal bioassays
DJ Brayden, V Stuettgen - European Journal of Pharmaceutical Sciences, 2021 - Elsevier
… the P app of the paracellular marker, FITC-dextran 4000 (FD4… H]-octreotide flux across isolated
rat colonic mucosae (iv) the … were efficacious at promoting transepithelial peptide flux, but …
rat colonic mucosae (iv) the … were efficacious at promoting transepithelial peptide flux, but …
Exposure to a nonionic surfactant induces a response akin to heat-shock apoptosis in intestinal epithelial cells: implications for excipients safety
… permeability as indicated by the release of LDH, internalization of FD4, and as a marker of
nuclear membrane permeability… components will likely promote immunogenic response in the …
nuclear membrane permeability… components will likely promote immunogenic response in the …
A Narrative Review on Non-Invasive Drug Delivery of Teriparatide: A Ray of Hope
N Mittal, G Sharma, OP Katare… - Critical Reviews™ in …, 2023 - dl.begellhouse.com
… of glycoprotein present in mucus enhances the mucoadhesive properties of thiolated chitosan.…
CriticalSorb™ promotes permeation of flux markers across isolated rat intestinal mucosae …
CriticalSorb™ promotes permeation of flux markers across isolated rat intestinal mucosae …
Nasal administration and plasma pharmacokinetics of parathyroid hormone peptide PTH 1-34 for the treatment of osteoporosis
RG Pearson, T Masud, E Blackshaw, A Naylor… - Pharmaceutics, 2019 - mdpi.com
… benefit from a permeation enhancer to promote absorption across the nasal mucosa into the
… liquid nasal spray formulation containing the permeation enhancer polyethylene glycol (15)-…
… liquid nasal spray formulation containing the permeation enhancer polyethylene glycol (15)-…
Development and in vivo evaluation of intranasal formulations of parathyroid hormone (1-34)
D Wang, Y Du, W Zhang, X Han, H Zhang, Z Wang… - Drug …, 2021 - Taylor & Francis
… permeation enhancer to effectively and safely promote the absorption of PTH(1-34) across
the nasal mucosa. … macromolecular drugs crossing the nasal and intestinal mucosa in phase I …
the nasal mucosa. … macromolecular drugs crossing the nasal and intestinal mucosa in phase I …
Enhanced permeation by amphiphilic surfactant is spatially heterogenous at membrane and cell level
R Cavanagh, S Shubber, D Vllasaliu… - Journal of Controlled …, 2022 - Elsevier
… in permeability enhancement technologies to achieve mucosal … of pulmonary or diseases of
intestinal tract. Efficient … that Kolliphor® HS15 promotes permeability across epithelial layers […
intestinal tract. Efficient … that Kolliphor® HS15 promotes permeability across epithelial layers […
Recent development of polymer nanomicelles in the treatment of eye diseases
R Cai, L Zhang, H Chi - Frontiers in bioengineering and …, 2023 - frontiersin.org
… time on the eye surface and promote corneal permeability. While the hydrophilic corneal …
attributes, augmented mucosal adhesiveness, elevated corneal permeation, and demonstrated …
attributes, augmented mucosal adhesiveness, elevated corneal permeation, and demonstrated …
Recombinant expressing angiopep-2 fused anti-VEGF single chain Fab (scFab) could cross blood–brain barrier and target glioma
X Ji, H Wang, Y Chen, J Zhou, Y Liu - AMB Express, 2019 - Springer
… However, the poor permeability of the macromolecules across the blood–brain barrier,
determined by multifactorial anatomical and physiological milieu, restricts the clinical therapeutic …
determined by multifactorial anatomical and physiological milieu, restricts the clinical therapeutic …