The function of cumulus cells in oocyte growth and maturation and in subsequent ovulation and fertilization

B Turathum, EM Gao, RC Chian - Cells, 2021 - mdpi.com
… the oocyte form the cumulus-oocyte complex (COC). This … The interactions between oocyte
and CCs involve a gap … During oocyte maturation, GDF9 and BMP15 act upon CCs to induce …

Intercellular communication in the cumulusoocyte complex during folliculogenesis: A review

J Xie, X Xu, S Liu - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
… Cutting off this RNA transmission can cause impaired oocyte development and a significant
… Exploring cell interactions during follicular development can help us better understand the …

Oocyte-cumulus cells crosstalk: New comparative insights

CA Martinez, D Rizos, H Rodriguez-Martinez… - Theriogenology, 2023 - Elsevier
oocyte development and folliculogenesis. This review will mainly focus on the reciprocal
interaction between oocytes and cumulus cells during the … called the cumulusoocyte complex (…

Transcriptomics of cumulus cells–a window into oocyte maturation in humans

BA Wyse, N Fuchs Weizman, S Kadish… - Journal of Ovarian …, 2020 - Springer
… The present sibling cumulus-oocyte-complex (COC) cohort study aimed at defining … are
altered throughout oocyte maturity, thus allowing for the interpretation of the complex interactions

Mammalian cumulus-oocyte complex communication: a dialog through long and short distance messaging

M Marchais, I Gilbert, A Bastien, A Macaulay… - Journal of Assisted …, 2022 - Springer
… In the ovarian follicular compartment, different cell types interact with each other in ways that
… but the mutual interdependency is a fundamental aspect of oocyte development and fertility. …

FGF2/FGFR signaling promotes cumulusoocyte complex maturation in vitro

C Du, JS Davis, C Chen, Z Li, Y Cao, H Sun… - …, 2021 - rep.bioscientifica.com
development and oocyte maturation in mammals. However, the expression patterns of the
ligand (FGF2) and receptors (FGFRs) in murine cumulus-oocyte complexes (… and interactions

Oocyte competence biomarkers associated with oocyte maturation: a review

B Sirait, B Wiweko, AA Jusuf, D Iftitah… - Frontiers in cell and …, 2021 - frontiersin.org
… several cumulus-oocyte complex (COC) biomarkers in evaluating … oocyte maturation and
are hereby assorted based on the processes that they associate with during oocyte maturation. …

Unlocking the mysteries of the cumulus-oocyte complex—a critical cellular partnership for developmental competence

J Buratini, P Comizzoli - Journal of Assisted Reproduction and Genetics, 2019 - Springer
oocyte maturation in vivo. For many decades, cellular and molecular mechanisms during
oocyte maturation … This has led to the development of in vitro maturation (IVM), which has been …

The bovine cumulus proteome is influenced by maturation condition and maturational competence of the oocyte

J Walter, C Monthoux, C Fortes, J Grossmann… - Scientific reports, 2020 - nature.com
… proteome of individual cumulus-oocyte complexes (COCs) with … -receptor interaction proteins
play a role in post-maturation … cells and are possible oocyte maturation factors. Journal of …

Nurturing the egg: the essential connection between cumulus cells and the oocyte

C Robert - Reproduction, Fertility and Development, 2021 - CSIRO Publishing
… of developmental competence by oocytes maturing in the … on which the cumulusoocyte
complexes were deposited had … interconnectivity, without which oocyte growth and acquisition of …