Curcumin activates the Nrf2 pathway and induces cellular protection against oxidative injury
M Ashrafizadeh, Z Ahmadi… - Current Molecular …, 2020 - ingentaconnect.com
… Curcumin induces Nrf2 nuclear translocation and prevents glomerular hypertension,
hyperfiltration, oxidant stress, and the decrease in antioxidant enzymes in 5/6 nephrectomized rats. …
hyperfiltration, oxidant stress, and the decrease in antioxidant enzymes in 5/6 nephrectomized rats. …
Curcumin reverses diabetic nephropathy in streptozotocin-induced diabetes in rats by inhibition of PKCβ/p66Shc axis and activation of FOXO-3a
… In conclusion, Curcumin prevents kidney damage in diabetic rats by activating Nrf2, inhibiting
Nf-κB… In addition, Curcumin induced the nuclear translocation of FOXO3a in melanoma and …
Nf-κB… In addition, Curcumin induced the nuclear translocation of FOXO3a in melanoma and …
[HTML][HTML] Nrf2 regulation by curcumin: molecular aspects for therapeutic prospects
SH Shahcheraghi, F Salemi, N Peirovi, J Ayatollahi… - Molecules, 2021 - mdpi.com
… prevented by curcumin mainly due to promoting the Nrf2 … found that curcumin induced the
nuclear translocation of Nrf2 in … autoregulation, proteinuria and hypertension. The protective …
nuclear translocation of Nrf2 in … autoregulation, proteinuria and hypertension. The protective …
[HTML][HTML] Protective role of Nrf2 in renal disease
M Guerrero-Hue, S Rayego-Mateos… - Antioxidants, 2020 - mdpi.com
… Moreover, the Nrf2 inducer curcumin improved the nephrotoxic … Sodium polysulfide induced
nuclear translocation of Nrf2 … upregulation of Nrf2 with proteinuria and high blood pressure. …
nuclear translocation of Nrf2 … upregulation of Nrf2 with proteinuria and high blood pressure. …
Role of curcumin in ameliorating hypertension and associated conditions: a mechanistic insight
… and alters mitochondrial permeability which hinders respiratory chain reactions [… Nrf2 from
Keap1 and its translocation to the nucleus. Glomerular high blood pressure and hyperfiltration …
Keap1 and its translocation to the nucleus. Glomerular high blood pressure and hyperfiltration …
Protective effects of curcumin and its analogues via the Nrf2 pathway in metabolic syndrome
S Rajabi, M Darroudi, K Naseri… - Current Medicinal …, 2024 - ingentaconnect.com
… of flavonoids li e curcumin in preventing metabolic diseases. … Due to the nuclear translocation
of Nrf2, hyperfiltration, renal … of the glomeruli, such as glomerular hypertension and hy…
of Nrf2, hyperfiltration, renal … of the glomeruli, such as glomerular hypertension and hy…
[HTML][HTML] Oxidative stress and NRF2/KEAP1/ARE pathway in diabetic kidney disease (DKD): new perspectives
… carbohydrate metabolism and prevent the development … blood pressure and total cholesterol
in DKD patients. The same authors also pointed out a drawback of this analysis; curcumin …
in DKD patients. The same authors also pointed out a drawback of this analysis; curcumin …
The pivotal role of nuclear factor erythroid 2-related factor 2 in diabetes-induced endothelial dysfunction
A Karan, E Bhakkiyalakshmi, R Jayasuriya… - Pharmacological …, 2020 - Elsevier
… Renal hyperfiltration mainly occurs due to the dilation of … was induced by SFN mediated
nuclear translocation of Nrf2 [91]. … Curcumin (CUR) is a popular spice, turmeric used in Asian …
nuclear translocation of Nrf2 [91]. … Curcumin (CUR) is a popular spice, turmeric used in Asian …
Filtering through the role of NRF2 in kidney disease
… of using NRF2 inducing compounds to alleviate ROS to prevent or … Upregulation of NRF2
with curcumin was shown to reduce … of glomerular hypertension (increased glomerular capillary …
with curcumin was shown to reduce … of glomerular hypertension (increased glomerular capillary …
[HTML][HTML] Anti-viral potential and modulation of Nrf2 by curcumin: pharmacological implications
… are cured by curcumin, Nrf2 activation prevented glomerular hypertension, hyperfiltration,
and … Recent studies have indicated that curcumin could activate nuclear translocation of Nrf2 …
and … Recent studies have indicated that curcumin could activate nuclear translocation of Nrf2 …