Somatic and germline genomics in paediatric acute lymphoblastic leukaemia

CH Pui, KE Nichols, JJ Yang - Nature reviews Clinical oncology, 2019 - nature.com
… and, hence, might differ between various clinical trials. Moreover, the prognosis of the 3%
of … a variety of cancers, including bone and soft-tissue sarcomas, brain tumours, early onset …

Impact of Neurapheresis system on intrathecal cerebrospinal fluid dynamics: a computational fluid dynamics study

M Khani, LR Sass, AR McCabe… - Journal of …, 2020 - asmedigitalcollection.asme.org
… Empirical models limit our ability to investigate CSF filtration technologies, highlighting
the need for a computational tool. Human clinical trials have been conducted (PILLAR trial [30,31])…

Next-generation characterization of the cancer cell line encyclopedia

M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov… - Nature, 2019 - nature.com
… responses, here we have expanded the characterizations of cancer cell lines to include …
and reverse-phase protein array data for 1,072 cell lines from individuals of various lineages and …

Oncogenic K-Ras Alleles and Their Genetic Interactors in Mouse Models of Colorectal Cancer

YJ Lin - 2020 - search.proquest.com
… Sunniva, our friendship will predate almost every other relationship I will ever have, you were
my … inhibition is contested by other retrospective analyses and one prospective clinical trial

Personalized therapy of neurological disorders

KK Jain, KK Jain - Textbook of Personalized Medicine, 2021 - Springer
… virtual clinical trial design enables collection of real-time information at each stage of the trial
as … Genotype-specific responses of AD patients to a drug or combination of drugs has been …

An organoid platform to study alveolar stem cells in lung generation and cancer

SSJ Naranjo - 2020 - dspace.mit.edu
… We have come a long way from the days you would chase me down the hall for scaring
you. I look forward to celebrating our time in the lab like we used to back when you would hold …

[图书][B] Functional Genomics Identify Novel Therapeutic Vulnerabilities in Retinoblastoma

A Aubry - 2020 - search.proquest.com
Retinoblastoma is a pediatric cancer caused by loss of the RB1 tumor suppressor gene or,
in rare cases, amplification of the MYCN oncogene. Improved treatments are required to …

Viral-based animal models in polyglutamine disorders

C Henriques, MM Lopes, AC Silva, DD Lobo, RA Badin… - Brain, 2024 - academic.oup.com
… In an effort to complement and deepen our knowledge, researchers have also developed
animal models of polyglutamine disorders employing viral vectors. Viral vectors have been …

[PDF][PDF] Cyfip2 Controls the Acoustic Startle Threshold and Visually Mediated Behaviors.

JC Deslauriers - 2023 - repository.lib.ncsu.edu
… Alexa, Josh, and Chase thank you for being not only siblings I can be proud of, but ones that
… We replicate those findings here, using a 60-stimulus assay consisting of 10 trials at each of …