… including colorectal cancer (CRC). CRC, being one of the most common cancers worldwide,
… the evidence that links redox stress to the development of CRC and assimilate the most up-…

… transpeptidase (GGT), Glutathione peroxidase (GPX), microsomal prostaglandin E synthase-1
(mPGES-1), 15-hydroxyprostaglandin dehydrogenase (15-PGDH) and cyclooxygenase-2 (…

… Cyclooxygenase-2 (COX2) mRNA represents a key biomarker for identifying subjects with
colorectal cancer (… ) is extensively developed for the amplification of nucleic acids; however, its …

… -α executes a key function in the production of intestinal polyps in adenomatous polyposis coli
… progression was exhibited when TNF-α was blocked in mice induced with colon tumors by …

… , tumor mass development, and dissemination. Cyclooxygenase-2 (COX-2) has an important
role, not only in angiogenic mechanisms, but also in favoring cancer invasion. Indeed …

… The NF-κB pathway also serves as an important regulator of the genes encoding TNF
and Cyclooxygenase-2 (COX-2),50 which are often highly overexpressed in inflammatory …

… [29] reported that HCT116 cells incubated with adiponectin had a lower expression of
cyclooxygenase-2 (COX-2) mRNA, but higher expression of T-cadherin. This finding was …

… Given that cyclooxygenase-2 (COX-2) is a known downstream effector of Aspirin … of colon
cancer [42]. Here, we identified an unexpected function of Aspirin in sensitizing colon cancer …

… synthesis and has a key role in the tumorigenesis of colorectal cancer. HMG Co-A R is
overexpressed/high activity from normal epithelium to colorectal tumors of early or advanced …

… which tumors develop. Chronic inflammation can initiate and sustain tumor development,
and in turn, a tumor constantly secretes inflammatory molecules that insures its progression…