[HTML][HTML] Allomyrina dichotoma larva extract attenuates free fatty acid-induced lipotoxicity in pancreatic beta cells

K Kim, MK Kwak, GD Bae, EY Park… - Nutrition Research …, 2021 - synapse.koreamed.org
… The inflammatory response of beta cells stimulates the expression of inducible nitric oxide
synthase and the overproduction of NO, resulting in cell damage [24]. Therefore, the nitrite …

Raspberry and blackberry act in a synergistic manner to improve cardiac redox proteins and reduce NF-κB and SAPK/JNK in mice fed a high-fat, high-sucrose diet

RS Najjar, D Knapp, D Wanders, RG Feresin - Nutrition, Metabolism and …, 2022 - Elsevier
… whether berries could attenuate the detrimental effects of a … or paracrine fashion, exacerbating
the inflammatory process [12]. … Cyclophilin expression levels were unchanged in response

The Immune Escape Mechanisms of Mycobacterium Tuberculosis

W Zhai, F Wu, Y Zhang, Y Fu, Z Liu - International journal of molecular …, 2019 - mdpi.com
… Besides, we also elaborate on the adaptive immune response … Through the inhibition
lipopolysaccharide-induced NF-κB-… P19 lipoprotein on the cell wall of attenuated MTB stimulates …

The emerging role of mtDNA release in sepsis: Current evidence and potential therapeutic targets

Q Hong, S Zhu, Y Yu, Y Ren, L Jin… - Journal of Cellular …, 2024 - Wiley Online Library
… lead to cellular dysfunction, disruption of aerobic respiration, and … immune response, which
is the primary agent responsible for … binding, immune response activation, and bloodstream …

Molecular signaling pathway targeted therapeutic potential of thymoquinone in Alzheimer's disease

FZ Khan, MS Mostaid, MNH Apu - Heliyon, 2022 - cell.com
… Till date, the established forms of treatment are only symptomatic in nature and are mainly
focused on counterbalancing the neurotransmitter disturbance features of the disease [ …

Gouty arthritis involves impairment of autophagic degradation via cathepsin D inactivation-mediated lysosomal dysfunction that promotes apoptosis in macrophages

YH Chen, WY Chen, CL Yu, CY Tsai… - Biochimica et Biophysica …, 2023 - Elsevier
… crystal-induced inflammatory response, whereas induction of … formation in both primary
and transformed macrophages, … of CTSD with PA did not attenuate MSU crystal-induced cell …

The targeted impact of flavones on obesity-induced inflammation and the potential synergistic role in cancer and the gut microbiota

M Sudhakaran, AI Doseff - Molecules, 2020 - mdpi.com
… browning, modulating immune responses in the adipose … Hence, a disrupted
macrophage–adipocyte crosstalk results … at 10–50 μM by attenuating the accumulation of …

[HTML][HTML] Fisetin nanoparticles protect against PM2. 5 exposure-induced neuroinflammation by down-regulation of astrocytes activation related NF-κB signaling …

MX Xu, CX Ge, Q Li, DS Lou, LF Hu, Y Sun… - Journal of Functional …, 2020 - Elsevier
… occurrence of metabolic disturbance and neuroinflammation, … is associated with the
inflammatory process in brain. The key … .5-induced inflammatory responses in primary astrocytes. …

[HTML][HTML] Pathologic sequelae of vascular cognitive impairment and dementia sheds light on potential targets for intervention

AE Linton, EM Weekman, DM Wilcock - Cerebral Circulation-Cognition and …, 2021 - Elsevier
… IL-12 in a lipopolysaccharide induced mouse model of sepsis [… NF-Kβ mediated pro-inflammatory
response while in a human … was attenuated, resulting in reduced cerebral blood flow, a …

Schistosoma japonicum Cystatin Alleviates Sepsis Through Activating Regulatory Macrophages

H Xie, L Wu, X Chen, S Gao, H Li, Y Yuan… - Frontiers in Cellular …, 2021 - frontiersin.org
immune responses to reduce deleterious inflammatory immune responses and stimulate
regulatory responses, … and swelling, inflammatory cell infiltration, disrupted or disordered tissue …