Tubular mitochondrial dysfunction, oxidative stress, and progression of chronic kidney disease

M Fontecha-Barriuso, AM Lopez-Diaz… - Antioxidants, 2022 - mdpi.com
… from a systemic inflammatory response to bacterial or viral (eg… 1 (mdivi-1), attenuated tubular
injury and tubular cell death in … The inhibition of cyclophilin D (CypD) with cyclosporine A or …

Targeting mitochondrial metabolites and nucleic acids as an anti-inflammatory strategy

Y Min, LAJ O'Neill - Frontiers in Drug Discovery, 2023 - frontiersin.org
… pathogens and the immune response to tissue injury. During … (ANT) and cyclophilin D and
mitochondrial outer membrane (… In a mouse model of SLE inflammation was attenuated after …

Anhydroexfoliamycin, a Streptomyces Secondary Metabolite, Mitigates Microglia-Driven Inflammation

S Gegunde, A Alfonso, R Alvarino… - ACS Chemical …, 2021 - ACS Publications
… We have tested the Streptomyces derivative on primary cortical … –brain barriers (BBB)
disruption, allowing lymphocytes to … AE inhibits the inflammatory response in activated microglia. …

Implications of oxidative stress and potential role of mitochondrial dysfunction in COVID-19: therapeutic effects of vitamin D

N de Las Heras, VM Martín Giménez, L Ferder… - Antioxidants, 2020 - mdpi.com
… in order to attenuate the antiviral immune response, as shown … The term oxidative stress
refers to a disturbance in the oxidant… primary cortical cell culture, vitamin D was able to attenuate

Aloe-emodin from Sanhua Decoction inhibits neuroinflammation by regulating microglia polarization after subarachnoid hemorrhage

H Liu, D Guo, J Wang, W Zhang, Z Zhu, K Zhu… - Journal of …, 2024 - Elsevier
… AE, as one ingredient of SHD, can alleviate the inflammatory response and protecting neurons
… Nevertheless, whether AE attenuates brain injury after SAH occurrence remains unravel. …

Protection against amyloid-β oligomer neurotoxicity by small molecules with antioxidative properties: potential for the prevention of Alzheimer's disease dementia

W Araki, F Kametani - Antioxidants, 2022 - mdpi.com
… -related protein 1 (Drp1), cyclophilin D (CypD), and amyloid-… that HT treatment attenuated
oxidative stress responses in the … -κB, which is involved in inflammatory responses as a main …

[HTML][HTML] Effects of dietary rumen-protected choline supplementation to periparturient dairy cattle on inflammation and metabolism in mammary and liver tissue during …

TH Swartz, BJ Bradford, LK Mamedova… - Journal of Dairy Science, 2024 - Elsevier
inflammatory responses to LPS and mitigate the negative systemic effects of inflammation
that dietary RPC supplementation would attenuate inflammation during an intramammary LPS …

[HTML][HTML] A diet rich in docosahexaenoic acid enhances reactive astrogliosis and ramified microglia morphology in apolipoprotein E epsilon 4-targeted replacement …

H Chappus-McCendie, MA Poulin… - Aging Brain, 2022 - Elsevier
… -7, lipopolysaccharide-induced CXC chemokine and … total lipids and have an attenuated
plasma response to n-3 PUFA … Breakdown of males and females in each group is provided …

Protective potential of hydroxysafflor yellow A in cerebral ischemia and reperfusion injury: An overview of evidence from experimental studies

L Yu, Z Jin, M Li, H Liu, J Tao, C Xu, L Wang… - Frontiers in …, 2022 - frontiersin.org
… , inflammatory response, neuronal apoptosis, BBB disruption and … primary neurons to
investigate the effect of HSYA on NMDAR-mediated neurotoxicity. HSYA was claimed to attenuate

Evaluation of natural compounds activity against oxidative stress and neuroinflammation. Implications for Alzheimer's disease

R Alvariño Romero - 2019 - minerva.usc.es
… Moreover, they were able to modulate the microglial inflammatory response, enhancing
their protective effects. The promising results obtained, mainly related to their antioxidant and …