Sirtuin 3 and mitochondrial permeability transition pore (mPTP): A systematic review
Y Yang, W Wang, Y Tian, J Shi - Mitochondrion, 2022 - Elsevier
… This review summarizes up-to-date evidence of the protective and inhibitory role of Sirt3
through deacetylating Cyclophilin D (CypD) on the mPTP aperture. Furthermore, we discuss the …
through deacetylating Cyclophilin D (CypD) on the mPTP aperture. Furthermore, we discuss the …
The Effect of Sulfur-Containing Compounds and Hydrogen Sulfide in the Modulation of the Immune Response
C Rodrigues - 2019 - search.proquest.com
… the physical barriers of the body initiates an inflammatory response, where a cascade of …
key regulator of the inflammatory response, mainly acting by attenuating NF-κB …
key regulator of the inflammatory response, mainly acting by attenuating NF-κB …
[HTML][HTML] Comparative proteomic study reveals the enhanced immune response with the blockade of interleukin 10 with anti-IL-10 and anti-IL-10 receptor antibodies in …
G Ni, S Chen, J Yuan, SF Cavezza, MQ Wei, H Li… - Plos one, 2019 - journals.plos.org
… primary function of IL-10 is to limit the amplitude of the immune response to avoid excessive
immune … It has been reported that elevated ARHGDIB was able to attenuate HIV-1 infection …
immune … It has been reported that elevated ARHGDIB was able to attenuate HIV-1 infection …
[HTML][HTML] Alpha-1-antitrypsin enhances primary human macrophage immunity against non-tuberculous mycobacteria
X Bai, A Bai, JR Honda, C Eichstaedt… - Frontiers in …, 2019 - frontiersin.org
… (56) showed that caspase-3 inhibition with two different caspase-3 inhibitors (z-VAD-fmk
and z-DEVD-fmk) abrogated lipopolysaccharide-induced NFκB activation in a mouse …
and z-DEVD-fmk) abrogated lipopolysaccharide-induced NFκB activation in a mouse …
[HTML][HTML] Platelet innate immune receptors and TLRs: a double-edged sword
T Ebermeyer, F Cognasse, P Berthelot… - International journal of …, 2021 - mdpi.com
… , via their TLRs, to immune response and inflammation, these receptors also participate in
… However, it can also occur independently from apoptosis and become primary. Primary and …
… However, it can also occur independently from apoptosis and become primary. Primary and …
[HTML][HTML] Necroptosis in hepatosteatotic ischaemia-reperfusion injury
R Baidya, DHG Crawford, J Gautheron… - International journal of …, 2020 - mdpi.com
… potential therapeutic approaches to attenuate IR injury will be a … We also discuss the immune
responses triggered during … known to exaggerate microcirculatory disturbance in the liver […
responses triggered during … known to exaggerate microcirculatory disturbance in the liver […
Mitochondrial Dysfunction in Periodontitis and Associated Systemic Diseases: Implications for Pathomechanisms and Therapeutic Strategies
Y Deng, J Xiao, L Ma, C Wang, X Wang… - International Journal of …, 2024 - mdpi.com
… It arises from the complex interplay between pathogenic oral bacteria and host immune
response. Contrary to the previous view of “energy factories”, mitochondria have recently been …
response. Contrary to the previous view of “energy factories”, mitochondria have recently been …
[HTML][HTML] Therapeutic potential of paeoniflorin in atherosclerosis: a cellular action and mechanism-based perspective
… Cyclophilin D (CypD) plays a crucial role in protein folding (66). Walter et al. … responses
to the inflammatory process, effectively inhibit IL-6 production and thus attenuate inflammatory …
to the inflammatory process, effectively inhibit IL-6 production and thus attenuate inflammatory …
Weaning causes a prolonged but transient change in immune gene expression in the intestine of piglets
N de Groot, F Fariñas… - Journal of animal …, 2021 - academic.oup.com
… inflammatory response during the postweaning period in piglets. A 45-d study included 108
piglets (weaned at 22 d, … function is disrupted, an upregulation of pro-inflammatory cytokines …
piglets (weaned at 22 d, … function is disrupted, an upregulation of pro-inflammatory cytokines …
[HTML][HTML] Paeoniflorin attenuates oxidative stress injury and improves mitochondrial membrane potential in human EA. hy926 endothelial cell through p-eIF2α and …
TT Ou, CM Chuang, YM Leung, IT Lee… - Journal of Functional …, 2021 - Elsevier
… stress-related apoptosis via three primary molecular sensors, … Our results indicated that H
2 O 2 induced Δψm disruption, … The role of cyclophilin D (CypD), as a physiological mediator …
2 O 2 induced Δψm disruption, … The role of cyclophilin D (CypD), as a physiological mediator …