… steroids, representing the therapy of choice in idiopathic … Peficitinib prevented the
cytokine-induced phosphorylation of … IL-13, IFN-γ and TNF-α from PBMCs of SSc patients. …

… the potential to inhibit cytokines and treat the cytokine storm. A … ), suppress (immunosuppressants)
or modulate various aspects … of corticosteroids downregulate proinflammatory cytokine …

… and improving oxidative stress through modulation of TGF-β/… the release of inflammatory
downstream cytokines IFN-γ, IL-13 … of starting corticosteroid therapy before or at the time of lung …

… on modulating the immune system to effectively treat disease. … using corticosteroids with or
without immunosuppressive drugs [… Interferon-γ (IFN-γ) is an endogenous cytokine involved in …

… of IFN-γ, which has been shown to attenuate fibrosis [53] by … fibrosis via the production of
pro-inflammatory cytokines such … pathways, including the modulation of several developmental …

… are associated with modulation of cytokines and growth factors… , PFD belongs to the
immunosuppressive drug class. In 2011, … , and prednisolone to successfully treat patients with post-…

… SP-D after CYC and prednisolone treatment (below 200 ng/ml) … Indeed, this modulation is
not specific to SSc and can be found … , producers of IFN-γ, an important cytokine in scleroderma …

… Patients who were treated with corticosteroids and/or immunosuppressive agents were … of
the expression of PXN decreased secretions of IFN-γ and TNF-α in activated NK cells (25). In …

… cell activation and an abnormal inflammatory cytokine response that exacerbates local …
-19 presentations and clinical outcomes, cytokines such as interleukin-1b (IL-1b), IL-6, IL-8, …

… cytokines are involved throughout the process of lung fibrosis. The … patients with idiopathic
pulmonary fibrosis undergoing treatment with steroids, immunosuppressants, and IFN-γ 1b…