… Therefore, the aim of this study was to develop a simple and clear method to predict …
apoptotic cells, DNA-PKcs is cleaved by a CPP32-like apoptotic protease [20] or ICE-like protease …

… A caspase contains a nucleophilic cysteine in its active site that attacks a target protein after
… as a cysteine protease is the initiator of apoptosis process in C. elegans and CED-4 protein …

… interleukin-1β converting enzyme (ICE) [8]. Multiple … and a large and small catalytic subunit.
Initiator caspases have … and Rho-associated coiled coil containing protein kinase 1 (ROCK1). …

… with Protease inhibitor cocktail (Thermo Fisher Scientific) on ice … response and p53
transcriptional targets among the DE … to an activator of p53-dependent apoptosis nutlin-3 [70] that …

… binding and stabilization of a catalytic subunit of PKA by hydralazine … and apoptosis and are
involved in calcium buffering 4,5 . … with trypsin and washed once using ice-cold PBS buffer. …

… with DNA-dependent protein kinase catalytic subunit (DNA-PKcs) … Given the critical role of
apoptosis in radioresistance, we … cells were trypsinized and washed with ice-cold PBS. Next, …

… apoptosis and was found to have significant homology to ICE. … anti-apoptotic transcription
factor and identified several target … The Ras-Raf-MEK-ERK, a Mitogen-activated protein kinase …

… transition holes, can initiate Caspase-dependent apoptosis. The apoptosome is a complex
formed when cytochrome-c combines with apoptotic protease activating factor-1 (Apaf-1), pro-…

… Receptor-interacting protein kinase 1 (RIPK1) is a key … that one regulatory subunit could
target different catalytic subunits to … After 30 min incubation on ice, the cells were centrifuged at …

… DNA-dependent protein kinase catalytic subunit (DNA-PKcs), … hypothesized that DNA-PKcs
may trigger apoptotic signals in … amplifier of tubular death and a promising therapeutic target. …