The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… of DNA methylation in embryonic, germline and somatic cell development. Finally, we provide
insights into DNA methylation … into the patterning of DNA methylation during development. …

[HTML][HTML] DNA methylation: a historical perspective

AL Mattei, N Bailly, A Meissner - Trends in Genetics, 2022 - Elsevier
… rapidly growing number of base-resolution methylation maps. Despite this, several … of DNA
methylation patterns remain under investigation. Here, we review the field of DNA methylation

The DNA methylation landscape in cancer

K Skvortsova, C Stirzaker, P Taberlay - Essays in biochemistry, 2019 - portlandpress.com
… into DNA methylation dynamics and remodeling in tumorigenesis. In this review, we describe
the distribution of DNA methylation and DNA … Finally, we discuss DNA methylation profiling …

[HTML][HTML] Sarcoma classification by DNA methylation profiling

C Koelsche, D Schrimpf, D Stichel, M Sill… - Nature …, 2021 - nature.com
… Recently, we have extended the principle of methylation-based … Further, DNA
methylation-based profiling showed diagnostic … In this work, we aimed at developing a DNA

DunedinPACE, a DNA methylation biomarker of the pace of aging

DW Belsky, A Caspi, DL Corcoran, K Sugden… - Elife, 2022 - elifesciences.org
… Using Illumina EPIC array DNA methylation data from blood collected at age 45, we
developed DunedinPACE to provide a surrogate for the 20- year Pace of Aging. Briefly, we used …

QSER1 protects DNA methylation valleys from de novo methylation

G Dixon, H Pan, D Yang, BP Rosen, T Jashari… - Science, 2021 - science.org
… In an effort to discover regulators of DNA methylation at bivalent promoters in hESCs, we …
DNA methylation reporter system (26). Our screen identified not only known methylation

[HTML][HTML] RNA-directed DNA methylation

RM Erdmann, CL Picard - PLoS genetics, 2020 - journals.plos.org
DNA elements in plants by adding DNA methylation over new TE insertions and constantly
reinforcing DNA methylation … is unique to plants, using DNA methylation to silence TEs is a …

The DNA methylation landscape of advanced prostate cancer

SG Zhao, WS Chen, H Li, A Foye, M Zhang… - Nature …, 2020 - nature.com
… We next identified DNA methylation valleys (DMVs), broad regions of hypo-methylation
59,60 that are associated with either the activating histone mark H3K4me3 or the repressive …

[HTML][HTML] Dynamics of DNA methylation and its functions in plant growth and development

S Kumar, T Mohapatra - Frontiers in Plant Science, 2021 - frontiersin.org
… a balance between DNA methylation and demethylation is … /functions of DNA base methylation
and epigenetic regulation of … review discusses the dynamics of DNA methylation (cytosine/…

[HTML][HTML] DNA methylation cancer biomarkers: translation to the clinic

WJ Locke, D Guanzon, C Ma, YJ Liew… - Frontiers in …, 2019 - frontiersin.org
… The ability of circulating tumor DNADNA methylation cancer biomarkers used in clinical
practice across the application domains above, discuss what makes a suitable DNA methylation