DNA methylation and regulation of gene expression: Guardian of our health
GA Dhar, S Saha, P Mitra, R Nag Chaudhuri - The Nucleus, 2021 - Springer
… , the DNA methylation pattern in the genome undergoes … result of regulated balance between
de novo DNA methylation and … DNA methylation pattern that fine tunes tissue-specific gene …
de novo DNA methylation and … DNA methylation pattern that fine tunes tissue-specific gene …
Enhancer DNA methylation: implications for gene regulation
A Angeloni, O Bogdanovic - Essays in biochemistry, 2019 - portlandpress.com
DNA methylation involves the addition of a methyl group to the fifth carbon of the pyrimidine
cytosine ring (5-methylcytosine, 5mC). 5mC is widespread in vertebrate genomes where it is …
cytosine ring (5-methylcytosine, 5mC). 5mC is widespread in vertebrate genomes where it is …
Prokaryotic DNA methylation and its functional roles
… cellular events regulated by DNA methylation in prokaryotes, … regulating gene expression
or by modulating the expression … , and through this, methylation signals might be used to …
or by modulating the expression … , and through this, methylation signals might be used to …
DNA methylation: shared and divergent features across eukaryotes
… understanding of DNA methylation profiles and functions in different eukaryotic lineages. …
Recruitment of de novo cytosine methyltransferases is regulated by small RNAs and/or specific …
Recruitment of de novo cytosine methyltransferases is regulated by small RNAs and/or specific …
DNA methylation-free Arabidopsis reveals crucial roles of DNA methylation in regulating gene expression and development
L He, H Huang, M Bradai, C Zhao, Y You, J Ma… - Nature …, 2022 - nature.com
… We found that the EdU signal, a proxy for DNA replication and cell division, is dramatically
decreased in met1-9, and is virtually undetectable in mddcc (Fig. 6b), demonstrating that CG …
decreased in met1-9, and is virtually undetectable in mddcc (Fig. 6b), demonstrating that CG …
[HTML][HTML] Cellular response to endogenous DNA damage: DNA base modifications in gene expression regulation
DL Bordin, L Lirussi, H Nilsen - DNA repair, 2021 - Elsevier
… a program of regulatory events orchestrated by cellular signal transduction pathways that …
constitutes an active DNA demethylation pathway to reverse DNA methylation and maintain …
constitutes an active DNA demethylation pathway to reverse DNA methylation and maintain …
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… our knowledge of DNA methylation dynamics and heterogeneity … genetic analyses, it is
increasingly apparent that regulation … that DNA methylation affects splicing and gene expression, …
increasingly apparent that regulation … that DNA methylation affects splicing and gene expression, …
[HTML][HTML] Anything but ordinary–emerging splicing mechanisms in eukaryotic gene regulation
NH Gehring, JY Roignant - Trends in Genetics, 2021 - cell.com
… of splicing regulation are well … the regulation of gene expression. In this review, we summarize
the current principles of splicing regulation, including the impact of cis and trans regulatory …
the current principles of splicing regulation, including the impact of cis and trans regulatory …
Evolution of DNA methylome diversity in eukaryotes
… Despite DNA methylation being central to eukaryotic … been associated with constitutive gene
expression, with roles in … might not be directly associated with gene regulation. In contrast, …
expression, with roles in … might not be directly associated with gene regulation. In contrast, …
DNA methylation methods: Global DNA methylation and methylomic analyses
S Li, TO Tollefsbol - Methods, 2021 - Elsevier
… DNA methylation of promoters and distal regulatory regions control gene expression [2]. …
However, TLC fails to yield a signal of 5hmC with genomic DNA extracted from cancer cells and …
However, TLC fails to yield a signal of 5hmC with genomic DNA extracted from cancer cells and …