The DNA methylation landscape of advanced prostate cancer

SG Zhao, WS Chen, H Li, A Foye, M Zhang… - Nature …, 2020 - nature.com
DNA methylation patterns between primary prostate cancer (PCa) and benign prostate tissue,
… Metastatic castration-resistant prostate cancer (mCRPC) is the lethal form of the disease. …

[HTML][HTML] Epigenome-wide association study of prostate cancer in African Americans identifies DNA methylation biomarkers for aggressive disease

Y Xu, CW Tsai, WS Chang, Y Han, M Huang… - Biomolecules, 2021 - mdpi.com
… Our study suggests that leukocyte DNA methylation may be valuable biomarkers for aggressive
PCa and the identified differentially methylated genes provide biological insights into the …

[HTML][HTML] Advances in prognostic methylation biomarkers for prostate cancer

D Lam, S Clark, C Stirzaker, R Pidsley - Cancers, 2020 - mdpi.com
DNA methylation is a frequent alteration in the cancer genome and offers potential as a reliable
and robust biomarker… of DNA methylation biomarker studies in prostate cancer prognosis…

[HTML][HTML] Combined analysis and validation for DNA methylation and gene expression profiles associated with prostate cancer

Y Tong, Y Song, S Deng - Cancer Cell International, 2019 - Springer
… Some studies also showed that overexpressed FBP1 in prostate cancers can be as a tumor
biomarker [… The abnormal expression of ALP can be a biomarker for prostate cancer [92]. The …

[HTML][HTML] … of tumor tissue-derived DNA methylation biomarkers for the detection and therapy response evaluation of metastatic castration resistant prostate cancer in …

T Dillinger, R Sheibani-Tezerji, W Pulverer, I Stelzer… - Molecular Cancer, 2022 - Springer
… epigenetic biomarkers has been … DNA methylation-based biomarkers for non-invasive PCa
diagnostics. Based on experiments and in silico analyses we identified two DNA methylation

[HTML][HTML] Epigenetic analysis of circulating tumor DNA in localized and metastatic prostate cancer: evaluation of clinical biomarker potential

MT Bjerre, M Nørgaard, OH Larsen, SØ Jensen… - Cells, 2020 - mdpi.com
… In the present study, we identified three highly PCa specific DNA methylation biomarkers,
DOCK2, HAPLN3, and FBXO30, with no false positive signal from PBCs or plasma cfDNA from …

DNA framework-supported electrochemical analysis of DNA methylation for prostate cancers

S Chen, J Su, Z Zhao, Y Shao, Y Dou, F Li, W Deng… - Nano Letters, 2020 - ACS Publications
… the epigenetic biomarkers for discriminating prostate cancer and … DNA methylation levels
of 12 selected gene promoters in prostate cancer cell line, cancer tissues, serum from cancer

[HTML][HTML] Distinct DNA methylation patterns associated with treatment resistance in metastatic castration resistant prostate cancer

MR Peter, M Bilenky, A Davies, R Isserlin, GD Bader… - Scientific Reports, 2021 - nature.com
DNA methylation changes on genes expression, especially with the development of tNEPC-like
disease, we integrated DNA methylation … of these methylation patterns as biomarkers of …

epiCaPture: a urine DNA methylation test for early detection of aggressive prostate cancer

E O'Reilly, AV Tuzova, AL Walsh, NM Russell… - JCO precision …, 2019 - ascopubs.org
… Herein, we present the results of one of two DNA methylation panels … reporting of prognostic
biomarker research. The Epigenetic … In this urine PCa biomarker study, we evaluated the …

[HTML][HTML] Genome-wide plasma DNA methylation features of metastatic prostate cancer

A Wu, P Cremaschi, D Wetterskog… - The Journal of …, 2020 - Am Soc Clin Investig
… In keeping with this being a discovery analysis in the roadmap to development of a
methylation-based biomarker, we prioritized patients with sufficient vials to allow both genome and …