SChLAP1 promotes prostate cancer development through interacting with EZH2 to mediate promoter methylation modification of multiple miRNAs of chromosome 5 …
K Huang, Y Tang - Cell Death & Disease, 2021 - nature.com
… DNA methylation and histone methylation. For instance, the reduced miR-143/miR-145
expression in prostate cancer … biomarkers for prostate cancer diagnosis and drug development. …
expression in prostate cancer … biomarkers for prostate cancer diagnosis and drug development. …
Methylation of SRD5A2 promoter predicts a better outcome for castration-resistant prostate cancer patients undergoing androgen deprivation therapy
Z Wang, T Deng, X Long, X Lin, S Wu, H Wang, R Ge… - Plos one, 2020 - journals.plos.org
… Predictive biomarkers identifying CRPC patients who … DNA methylation is correlated with
cancer progression, our findings show that hypermethylation in the SRD5A2 promoter region, …
cancer progression, our findings show that hypermethylation in the SRD5A2 promoter region, …
CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer
… manner, depending on DNA methylation-orchestrated … promoter. We demonstrate that
CTCF deposition at this site as measured by DNA methylation level is highly variable in prostate …
CTCF deposition at this site as measured by DNA methylation level is highly variable in prostate …
Epigenetic modifications in prostate cancer
M Sugiura, H Sato, M Kanesaka… - … Journal of Urology, 2021 - Wiley Online Library
… , but is also reported to be a biomarker of early disease detection. In PC, … prostate tissues.
The expression of PLAU is normally repressed by DNA methylation, but the promoter region of …
The expression of PLAU is normally repressed by DNA methylation, but the promoter region of …
DNA methylation and cis-regulation of gene expression by prostate cancer risk SNPs
… of 147 prostate cancer risk SNPs. The … prostate cancer tissue and the adjacent normal
tissue which has not been done previously; we rigorously dissect the role of DNA methylation in …
tissue which has not been done previously; we rigorously dissect the role of DNA methylation in …
Epigenetics regulation of prostate cancer: Biomarker and therapeutic potential
R Ragavi, P Muthukumaran, S Nandagopal… - … Oncology: Seminars and …, 2023 - Elsevier
… DNA methylation is a stable genomic change which can be investigated noninvasively in …
DNA methylation is a promising CaP DNA biomarker because it is one of the earliest molecular …
DNA methylation is a promising CaP DNA biomarker because it is one of the earliest molecular …
A novel combined miRNA and methylation marker panel (miMe) for prediction of prostate cancer outcome after radical prostatectomy
SH Strand, E Bavafaye‐Haghighi… - … Journal of Cancer, 2019 - Wiley Online Library
… and miRNAs are attractive sources for biomarker discovery … combined miRNA and DNA
methylation multimarker panel … combined miRNA and DNA methylation biomarker panel (miMe) …
methylation multimarker panel … combined miRNA and DNA methylation biomarker panel (miMe) …
Known epigenetic biomarkers for prostate cancer detection and management: Exploring the potential of blood-based liquid biopsies
V Constâncio, D Barros-Silva, C Jerónimo… - Expert Review of …, 2019 - Taylor & Francis
… island promoters are methylated in cancer. DNA methylation-based PCa biomarkers are …
to the high prevalence of hypermethylation at specific gene promoters and these have been …
to the high prevalence of hypermethylation at specific gene promoters and these have been …
Differential gene methylation patterns in cancerous and non‑cancerous cells
K Kamińska, A Białkowska… - Oncology …, 2019 - spandidos-publications.com
… whether DNA methylation plays a role in the expression of these genes in prostate cancer
cells. … is a potential sensitive and specific prostate cancer biomarker in ctDNA isolated from the …
cells. … is a potential sensitive and specific prostate cancer biomarker in ctDNA isolated from the …
DNA methylation biomarkers for nasopharyngeal carcinoma
B Han, X Yang, P Zhang, Y Zhang, Y Tu, Z He, Y Li… - PLoS …, 2020 - journals.plos.org
… of nasopharyngeal carcinoma development. Although many studies detected certain genes
with abnormal DNA hypermethylation or hypomethylation in nasopharyngeal carcinoma, it is …
with abnormal DNA hypermethylation or hypomethylation in nasopharyngeal carcinoma, it is …