[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics

S Li, Y Peng, AR Panchenko - Current opinion in structural biology, 2022 - Elsevier
DNA methylation is strongly associated with mutation … between DNA methylation and
downstream signaling pathways at … that a reversible epigenetic mark - cytosine methylation–can …

Mechanisms of human DNA methylation, alteration of methylation patterns in physiological processes and oncology

A Sergeeva, K Davydova, A Perenkov, M Vedunova - Gene, 2023 - Elsevier
… /extracellular signal-regulated kinase (MAPK/ERK) signaling … which could lead to DNA
methylation aberrations by disrupting … in methylation patterns result in a wide range of biological

[HTML][HTML] DNA methylation reprogramming during mammalian development

Y Zeng, T Chen - Genes, 2019 - mdpi.com
… efficient erasure of global DNA methylation, is relevant in multiple biological processes.
In … that the paternal genome loses the 5mC signal before the onset of DNA replication [108,109], …

Active turnover of DNA methylation during cell fate decisions

A Parry, S Rulands, W Reik - Nature Reviews Genetics, 2021 - nature.com
… This diversity allows one external signal or induction of a … is used to break the reversibility
dictated by thermal equilibrium … , we will better understand the biological importance of DNAme …

[HTML][HTML] DNA methylation and regulation of gene expression: Guardian of our health

GA Dhar, S Saha, P Mitra, R Nag Chaudhuri - The Nucleus, 2021 - Springer
… the biological clock consequently disrupting DNA methylation … a key role in the classical
signal transduction pathway), INS (… DNA cytosine methylation once established, was irreversible

[HTML][HTML] Physical activity and DNA methylation in humans

WJ Światowy, H Drzewiecka, M Kliber… - International journal of …, 2021 - mdpi.com
DNA methylation is catalyzed by a family of DNA methyltransferases. This reversible DNA
… sucrose metabolism, or insulin signaling pathway, and hypermethylation in genes related to …

The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… In addition to the short-term effects of repressing transposable elements, DNA methylation
also promotes their irreversible genetic inactivation through mutagenic deamination. Finally, …

Functional implications of DNA methylation in adipose biology

X Ma, S Kang - Diabetes, 2019 - Am Diabetes Assoc
DNA methylation is a reversible epigenetic mark involving the covalent transfer of a methyl
… and ST2 mesenchymal precursor cell lines by upregulating canonical Wnt signaling (21,26). …

DNA methylation as a transcriptional regulator of the immune system

L Morales-Nebreda, FS McLafferty, BD Singer - Translational Research, 2019 - Elsevier
DNA methylation on a genome-wide scale (Table I). Because DNA methylation marks are
erased by molecular biology … (activation of signaling pathways, such as signal transducer and …

Sensitivity of transcription factors to DNA methylation

É Héberlé, AF Bardet - Essays in biochemistry, 2019 - portlandpress.com
… repressor functions and an optional signal-sensing domain, which … 5mC is a reversible
modification. It can be removed passively … gene expression in many biological processes such as …