Epigenetic mechanisms underlying prostate cancer radioresistance
C Macedo-Silva, R Benedetti, F Ciardiello… - … Epigenetics, 2021 - Springer
… epigenetically induced changes in radioresistant-like PCa cells and describes recently reported
targeted epigenetic therapies in pre… DNA methylation is the major epigenetic mechanism …
targeted epigenetic therapies in pre… DNA methylation is the major epigenetic mechanism …
[HTML][HTML] DNA methylation readers and cancer: mechanistic and therapeutic applications
N Mahmood, SA Rabbani - Frontiers in oncology, 2019 - frontiersin.org
… of DNA methylation readers or MBPs and provides an updated summary of their roles in the
context of cancer. … Epigenetic therapies (“Epi-therapies”) targeting the components of the …
context of cancer. … Epigenetic therapies (“Epi-therapies”) targeting the components of the …
Effects of propolis and phenolic acids on triple-negative breast cancer cell lines: Potential involvement of epigenetic mechanisms
… of known compounds as well as novel drugs for epigenetic therapy [43]. Overall, the docking
… reverted the DNA methylation of an important tumor suppressor gene. New studies are …
… reverted the DNA methylation of an important tumor suppressor gene. New studies are …
piR-31470 epigenetically suppresses the expression of glutathione S-transferase pi 1 in prostate cancer via DNA methylation
L Zhang, X Meng, C Pan, F Qu, W Gan, Z Xiang, X Han… - Cellular signalling, 2020 - Elsevier
… by piR-31470 in prostate cancer, which may possibly lead to the formulation of new ideas
and strategies with respect to epigenetic treatment of prostate cancer by targeting piRNAs. …
and strategies with respect to epigenetic treatment of prostate cancer by targeting piRNAs. …
The roles of epigenetics in cancer progression and metastasis
JF Chen, Q Yan - Biochemical Journal, 2021 - portlandpress.com
… DNA methyltransferase inhibitor, 5-azacytidine, and HDAC inhibitor, entinostat, in lung, breast,
and oesophageal cancer … Specifically, low-dose epigenetic therapy not only impedes the …
and oesophageal cancer … Specifically, low-dose epigenetic therapy not only impedes the …
The epigenetic drug discovery landscape for metabolic-associated fatty liver disease
… Here, we provide an up-to-date overview of current knowledge of three distinct but
interrelated epigenetic processes (DNA methylation, histone modification (methylation/acetylation), …
interrelated epigenetic processes (DNA methylation, histone modification (methylation/acetylation), …
DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load
… that DNA methylation aberration is an … epigenetic therapy are required when targeting these
tumours. Specifically, it needs to be tested whether methylation inhibitors or other epigenetic …
tumours. Specifically, it needs to be tested whether methylation inhibitors or other epigenetic …
Helicobacter pylori-induced DNA Methylation as an Epigenetic Modulator of Gastric Cancer: Recent Outcomes and Future Direction
JS Muhammad, MA Eladl, G Khoder - Pathogens, 2019 - mdpi.com
… Epigenetic treatment offers a potential therapy to treat chemo- and radio-resistant tumors; …
treatments are still in their infancy. Further studies are required to reveal epigenetic changes …
treatments are still in their infancy. Further studies are required to reveal epigenetic changes …
[HTML][HTML] Epigenetic clock: DNA methylation in aging
S Jiang, Y Guo - Stem cells international, 2020 - hindawi.com
… in DNA methylation level patterns and aging. In addition, we introduce the known mechanisms
by which DNA methylation … DNA methylation regulates aging, antiaging interventions and …
by which DNA methylation … DNA methylation regulates aging, antiaging interventions and …
[HTML][HTML] Current landscape of epigenetics in lung cancer: focus on the mechanism and application
YX Shi, DQ Sheng, L Cheng, XY Song - Journal of oncology, 2019 - hindawi.com
… epigenetic regulation, DNA methylation is by far the most studied and is responsible for gene
silencing and chromatin structure. DNA methylation … ., “Combination epigenetic therapy has …
silencing and chromatin structure. DNA methylation … ., “Combination epigenetic therapy has …