Cell-free nucleic acids and their emerging role in the pathogenesis and clinical management of inflammatory bowel disease
Z Kubiritova, J Radvanszky, R Gardlik - International Journal of Molecular …, 2019 - mdpi.com
… In addition, it was recently revealed that DNA methylation plays an important role in
autoimmune-related chronic inflammatory diseases [77]. DNA methylation is an important epigenetic …
autoimmune-related chronic inflammatory diseases [77]. DNA methylation is an important epigenetic …
DNA methylation aberrant in atherosclerosis
Y Dai, D Chen, T Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
… This review will discuss the abnormal changes of DNA methylation in AS, including genome-…
of epigenetic treatment, which may provide new direction and potential therapeutic targets …
of epigenetic treatment, which may provide new direction and potential therapeutic targets …
Epigenetics in breast cancer therapy—New strategies and future nanomedicine perspectives
V Buocikova, I Rios-Mondragon, E Pilalis… - Cancers, 2020 - mdpi.com
… epigenetic therapy of BC, focusing on the ability of epi-drugs to sensitize resistant cancer
cells to standard therapeutic … DNA methylation occurring in the promoter regions inhibits gene …
cells to standard therapeutic … DNA methylation occurring in the promoter regions inhibits gene …
Epigenetic mechanisms of resistance to immune checkpoint inhibitors
A Perrier, A Didelot, P Laurent-Puig, H Blons, S Garinet - Biomolecules, 2020 - mdpi.com
… We discussed earlier that altered DNA methylation profiles in cancer cells or immune cells
impinge on tumor-specific … Epigenetic treatments also target the linkage between DNA …
impinge on tumor-specific … Epigenetic treatments also target the linkage between DNA …
Epigenetic modifications of c-MYC: Role in cancer cell reprogramming, progression and chemoresistance
… transcription factor, epigenetic therapy might be one of the … DNA methyltransferases (DNMTs)
catalyze DNA methylation and regulate gene expression involved in colorectal carcinoma (…
catalyze DNA methylation and regulate gene expression involved in colorectal carcinoma (…
Epigenetics in hepatocellular carcinoma
GP Nagaraju, B Dariya, P Kasa, S Peela… - Seminars in cancer …, 2022 - Elsevier
… The DNA methylation plays a significant role in regulating gene expression. The epigenetic
DNA methylation … Even though the epigenetic therapeutic drugs targeting these pathways …
DNA methylation … Even though the epigenetic therapeutic drugs targeting these pathways …
Conserved DNA methyltransferases: a window into fundamental mechanisms of epigenetic regulation in bacteria
PH Oliveira, G Fang - Trends in microbiology, 2021 - cell.com
… DNA methylation is the epigenetic mark most commonly found … variety of functional roles,
including defense against foreign DNA, … DNA methyltransferases (MTases) are responsible for …
including defense against foreign DNA, … DNA methyltransferases (MTases) are responsible for …
Drug resistance in colorectal cancer: An epigenetic overview
… modification and DNA methylation. In this review, we discuss epigenetic regulation in CRC
… of preventing or reversing CRC drug resistance using epigenetic therapy in CRC treatment. …
… of preventing or reversing CRC drug resistance using epigenetic therapy in CRC treatment. …
The emerging role of the piRNA/piwi complex in cancer
Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
… , functions, and emerging roles in cancer, providing new … and piwi proteins in cancer
diagnosis and clinical treatment. … global DNA methylation and inhibiting tumor suppressor p16 …
diagnosis and clinical treatment. … global DNA methylation and inhibiting tumor suppressor p16 …
The epigenetic and transcriptional landscape of neuroendocrine prostate cancer
… fuel epigenetic/transcriptional changes as well as the current state of epigenetic therapies for
… In NEPC, perturbed DNA methylation patterning and expression of epigenetic remodeling …
… In NEPC, perturbed DNA methylation patterning and expression of epigenetic remodeling …