[HTML][HTML] Genome-wide association studies

E Uffelmann, QQ Huang, NS Munung… - Nature Reviews …, 2021 - nature.com
… , including the collection of DNA and phenotypic information … using power calculations in
software tools such as CaTS 14 … 132 and performing large-scale experimental perturbation of …

[HTML][HTML] Recommendations for choosing the genotyping method and best practices for quality control in crop genome-wide association studies

S Pavan, C Delvento, L Ricciardi, C Lotti, E Ciani… - Frontiers in …, 2020 - frontiersin.org
… species, and deliver an overview of bioinformatics tools that can be used to accomplish all
… used to interrogate complementary fragments from DNA samples and infer genotypes based …

[HTML][HTML] Confounding of linkage disequilibrium patterns in large scale DNA based gene-gene interaction studies

M Joiret, JM Mahachie John, ES Gusareva… - BioData mining, 2019 - Springer
… Reduction as one large-scale epistasis detection tool. Its … complex diseases in genome-wide
association studies (GWAS). The … The core idea of MB-MDR is to pool 2-locus genotypes …

[HTML][HTML] Epigenome-wide association studies: current knowledge, strategies and recommendations

MP Campagna, A Xavier, J Lechner-Scott, V Maltby… - Clinical …, 2021 - Springer
… , (2) there are many large-scale DNA banks of convenience … provides a powerful tool for
analysis of DNA methylation data … By pooling information from all CpGs limma moderates SE at …

GWAS Central: a comprehensive resource for the discovery and comparison of genotype and phenotype data from genome-wide association studies

T Beck, T Shorter, AJ Brookes - Nucleic acids research, 2020 - academic.oup.com
… the data, for example, large-scale meta-analyses have suggested … of identifying individuals
from pooled sources of summary-… The website search tools enable results for single studies to …

Low-bias manipulation of DNA oligo pool for robust data storage

Y Gao, X Chen, H Qiao, Y Ke, H Qi - ACS synthetic biology, 2020 - ACS Publications
large-scale DNA storage that requires amplification and sequencing of massive numbers of
DNA … Therefore, random access in a large-scale DNA oligo pool will be technically feasible …

Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests

N Barak, R Ben-Ami, T Sido, A Perri… - Science Translational …, 2021 - science.org
tools enabling efficient and rapid turnaround such as alerts, data analysis tools for the different
stages of pooling… PCR reaction roughly multiplies the amount of the targeted DNA in each …

[HTML][HTML] DNA-based assessment of genetic diversity in grassland plant species: Challenges, approaches, and applications

M Loera-Sánchez, B Studer, R Kölliker - Agronomy, 2019 - mdpi.com
… perspectives on using large-scale genetic diversity monitoring to … bulked DNA approach also
known as Pool-Seq [97], in which the … the power of genome-wide association studies [148]. …

Three assays for in-solution enrichment of ancient human DNA at more than a million SNPs

N Rohland, S Mallick, M Mah, R Maier… - … research, 2022 - genome.cshlp.org
… -wide association studies and that has been widely used in genome-wide studies of human
history. … Because the enriched ancient DNA libraries were sequenced in pools, we needed to …

[HTML][HTML] Efficient mixed model approach for large-scale genome-wide association studies of ordinal categorical phenotypes

W Bi, W Zhou, R Dey, B Mukherjee, JN Sampson… - The American Journal of …, 2021 - cell.com
… In genome-wide association studies, ordinal categorical phenotypes are widely used to
measure human behaviors, satisfaction, and preferences. However, because of the lack of …