… and Lrp both influence fimS inversion in the same direction, … DNA supercoiling/relaxation,
Lrp and Fis in determining the … and DNA is negatively supercoiled links fim switch inversion …

… The translocation of the elongation complex overwinds the DNA … DNA binding proteins,
including IHF and LRP, cooperate with DNA supercoiling to set and to reset the genetic switch …

… factor, provide a basis for a stochastic genetic switch that acts at random in each cell in the
… its neighbours by copies of an inverted repeat; adaptation proteins integrate the spacers. …

… on the five major proteins H-NS, FIS, IHF, Lrp and HU, for which … of RNA polymerase or stall
its translocation, while in some … DNA supercoiling-dependent modulation of the directionality …

… the ordering is related to the directionality of DNA replication (18). … by translocation of the
transcription machinery along the DNA … Lrp, like other DNA-binding proteins of the AsnC family, …

… of the fim genes encoding the structural proteins revealed that … found that lrp is required for
normal activity of the jim switch. … the direction of transcription) flanked by 9-bp inverted repeat …

… inversion of the fimS switch from the ON-to-OFF direction. It is … Lrp binds to two sites in or
near the fimS switch, where it acts … fimS switch of EPEC E2348/69 showed that this fim switch is …

… DNA supercoiling and nucleoid-associated proteins (NAPs) … , with small black arrows to
indicate the direction of transcription. … 2c) is not supported by these hns gene translocation data […

… Arrows indicate the direction of each reaction. (B to D) In vivo … IHF), and leucine-responsive
protein (LRP), in addition to the … intensity (total fim on and total fim off) to calculate the percent …

… phase variation, determined by the fim switch analysis, … factors; H-NS, IHF, and Lrp on the
expression of FimB and FimE … phase switching, is caused by the inversion of a 314 bp DNA …