Responsive neurostimulation as a novel palliative option in epilepsy surgery

M Inaji, T Yamamoto, K Kawai, T Maehara… - Neurologia medico …, 2020 - jstage.jst.go.jp
… According to the first report of direct stimulation to the human brain … seizures by direct brain
stimulation in response to detected … These data do not necessarily reflect daily or usual brain

Role of responsive neurostimulation and immunotherapy in refractory epilepsy due to autoimmune encephalitis: A case report

SH Chen, PK O'Dea, B Sianati… - Frontiers in neurology, 2022 - frontiersin.org
… laboratory findings of a young man with AE complicated by AAE … 20 mg twice daily,
levetiracetam 2,000 mg twice daily, … as detection-only change (red), treatment-only change (blue), …

Can Chronically Implanted iEEG Sense and Stimulation Devices Accelerate the Discovery of Neural Biomarkers?

KK Sellers, EF Chang - Intracranial EEG: A Guide for Cognitive …, 2023 - Springer
… The advent of chronically implanted neurostimulation … to chronically record iEEG from humans
during their daily lives. … to 100× higher compared to EEG [64], so detection of more subtle …

Responsive neurostimulation as a treatment for super-refractory focal status epilepticus: a systematic review and case series

LD Ernst, AM Raslan, A Wabulya, HW Shin… - Journal of …, 2023 - thejns.org
… on topic, in English, and human studies, as well as the ref… subclinical and discovered
incidentally with intracranial EEG. … the time from day of RNS implantation to day of SE resolution …

Electrical brain stimulation and continuous behavioral state tracking in ambulatory humans

F Mivalt, V Kremen, V Sladky, I Balzekas… - Journal of neural …, 2022 - iopscience.iop.org
… A small study of responsive neurostimulation with only … Intracranial EEG (iEEG) signal
changes between different … Short data drops account for up to 2.9 h of missing data every day (…

[HTML][HTML] Brain-responsive corticothalamic stimulation in the centromedian nucleus for the treatment of regional neocortical epilepsy

DE Burdette, MA Haykal, B Jarosiewicz, RR Fabris… - Epilepsy & Behavior, 2020 - Elsevier
… CMT and neocortical responsive stimulation, detection, and … The neurostimulator also stores
samples of intracranial EEG (… (minutes instead of hours per day), which might be expected to …

Human intracranial recordings reveal distinct cortical activity patterns during invasive and non-invasive vagus nerve stimulation

WL Schuerman, KV Nourski, AE Rhone, MA Howard… - Scientific reports, 2021 - nature.com
… in low frequency EEG power 4 . Non-invasive neuroimaging of … However, we also found
that, within the participants who … and the high degree of variability in response to comparable …

Early seizure detection for closed loop direct neurostimulation devices in epilepsy

M Dümpelmann - Journal of neural engineering, 2019 - iopscience.iop.org
… treatment of human epilepsy using direct neurostimulation. … evaluated on scalp or intracranial
EEG, patient individual or … , false detection rates are often counted per hour or per day, …

Analog Seizure Detection for Implanted Responsive Neurostimulation

AA Zaki, NC Parker, TY Kim, S Ishak, TE Stovall… - arXiv preprint arXiv …, 2021 - arxiv.org
… conditions, epilepsy affects 50 million people worldwide [1]. … day for less seizure-active
patients and up to 2000 times a … well, if not better, on intracranial EEG data albeit with some …

Initial case series of a novel sensing deep brain stimulation device in drug‐resistant epilepsy and consistent identification of alpha/beta oscillatory activity: A feasibility …

MMJ Chua, M Vissani, DD Liu, FL Schaper… - …, 2023 - Wiley Online Library
… (EEG) monitoring over 4 days revealed bursts of generalized (… was experiencing multiple
daily episodes (up to 6 daily) of 10 … Patient 4 was a 60-year-old man with seizures beginning at …