… Apoptotic cell death is usually a response to the cell’s … In acute renal failure, cell death may
be a direct … they are within the nucleus exert DAMP effects once released into the extracellular …

… immune response to microorganisms and endogenous danger … 8 activation or apoptotic
cell death in response to TNF or … demonstrate reduced kidney injury, cell death, inflammation …

… Sterile inflammation is a response to acute or chronic tissue injury … kidney diseases leading
to end-stage renal disease with … Figure 2 Different outcomes of cell death and DAMP release …

… Loss of renal function due to tubular cell death is … of DAMP generation and release during
AKI as well as their role in initiating the immune response and triggering loss of kidney function…

… Kidney disease progression as defined by a decline in GFR … Our understanding is that no
other cell death pathway … that were on the basis of the DAMP release as the exclusive immune-…

… danger-associated molecular patterns generated during … damages renal cells, resulting in
injury or cell death and the … and fibrotic responses in various kidney diseases including DKD, …

… -induced acute kidney injury is renal cell death. As such, … and therapies that combat kidney
failure and disease. These … is released from lysed cells functions as a DAMP that binds to the …

… either passively during cell death, or actively during NET … This recently identified DAMP
is mentioned within this review, … Within this review, we focus on two renal diseases in which …

… to cell death following renal IRI, with an emphasis on RN. … kidney injury may predispose
to chronic kidney disease and … DAMP” that contributes to both innate and adaptive immune …

… on the polarisation of the immune response. In this review, … background of DAMP release
during apoptosis, necroptosis, … DAMPs may significantly amplify the danger signal, since it was …