Brain-derived neurotrophic factor in brain disorders: focus on neuroinflammation

B Lima Giacobbo, J Doorduin, HC Klein… - Molecular …, 2019 - Springer
concentrations in their blood and brain. A current hypothesis suggests that these abnormal
BDNF levels … ], suggesting that reduced BDNF levels in the brain rather than a reduction in the …

Decreased serum brain-derived neurotrophic factor (BDNF) levels in patients with Alzheimer's disease (AD): a systematic review and meta-analysis

TKS Ng, CSH Ho, WWS Tam, EH Kua… - International journal of …, 2019 - mdpi.com
… One of the implications of this study is that decreased peripheral BDNF levels in AD could
serve as a baseline for future trials to examine the effectiveness of the trials in improving …

Plasma levels of brain-derived neurotrophic factor in patients with Parkinson disease: a systematic review and meta-analysis

F Rahmani, A Saghazadeh, M Rahmani, AL Teixeira… - Brain research, 2019 - Elsevier
… comparisons revealed that serum BDNF levels are significantly (P = 0.03) decreased in PD
… BDNF concentrations in serum, plasma or CSF in patients with PD, written in English, with …

Associations between serum and plasma brain-derived neurotrophic factor and influence of storage time and centrifugation strategy

AK Gejl, C Enevold, A Bugge, MS Andersen… - Scientific reports, 2019 - nature.com
… and centrifugation strategy on brain-derived neurotrophic factor (BDNF) levels in human …
we found that serum contained far higher concentrations of BDNF than plasma and observed no

[HTML][HTML] Brain-derived neurotrophic factor signaling in depression and antidepressant action

E Castrén, LM Monteggia - Biological psychiatry, 2021 - Elsevier
… , a decrease in serum BDNF levels is not specific to depression: serum BDNF levels have
been reported to be decreased … , but antidepressants accumulate in brain, and concentrations

[HTML][HTML] Modulation of serum brain-derived neurotrophic factor by a single dose of ayahuasca: observation from a randomized controlled trial

RN Almeida, ACM Galvão, FS da Silva… - Frontiers in …, 2019 - frontiersin.org
that serum brain-derived neurotrophic factor (BDNF) levels … also caused by decreased
neuroplasticity and neurogenesis … BDNF and cortisol serum concentrations were converted to …

Lactate mediates the effects of exercise on learning and memory through SIRT1-dependent activation of hippocampal brain-derived neurotrophic factor (BDNF)

L El Hayek, M Khalifeh, V Zibara… - Journal of …, 2019 - Soc Neuroscience
… disorders characterized by a decrease in Bdnf expression and … that is produced during
exercise, crosses the bloodbrain barrier … concentrations are consistent with lactate plasma levels

[HTML][HTML] Brain-derived neurotrophic factor: a key molecule for memory in the healthy and the pathological brain

M Miranda, JF Morici, MB Zanoni… - Frontiers in cellular …, 2019 - frontiersin.org
… this neurotrophin could have clinical relevance. We propose that, although BDNF may not be
a … There are several reasons to think that a decrease in BDNF levels could be detrimental to …

Screening of brain-derived neurotrophic factor (BDNF) single nucleotide polymorphisms and plasma BDNF levels among Malaysian major depressive disorder …

AF Aldoghachi, YS Tor, SZ Redzun, KAB Lokman… - PLoS …, 2019 - journals.plos.org
decrease in the plasma BDNF level of the cases as compared to controls (p<0.0001) was
observed. However, there was no … in this study was not sensitive to mature BDNF alone but, it …

[HTML][HTML] Brain-derived neurotrophic factor and its potential therapeutic role in stroke comorbidities

W Liu, X Wang, M O'Connor, G Wang, F Han - Neural plasticity, 2020 - ncbi.nlm.nih.gov
but not BDNF alone, was able to restore the neuronal cell density in the CA1 region and
significantly reduce … to learn the effective range of concentrations and functional time windows in …