The emerging clinical potential of circulating extracellular vesicles for non-invasive glioma diagnosis and disease monitoring

S Hallal, S Ebrahimkhani, B Shivalingam… - Brain tumor …, 2019 - Springer
… is a key microRNA significantly enriched in glioblastoma EVs [… end of miRNAs and direct
them to the exosomal compartment [… as a non-invasive alternative to tissue biopsies and allow

Profiling of novel circulating microRNAs as a non-invasive biomarker in diagnosis and follow-up of high and low-grade gliomas

A Tabibkhooei, M Izadpanahi, A Arab… - Clinical Neurology and …, 2020 - Elsevier
… a novel miRNA signature in plasma of GBM patients as a … suggest that plasma exosomal
miRNAs can have potential … et al. during their deep sequencing study of childhood acute …

Circulating biomarkers in patients with glioblastoma

J Müller Bark, A Kulasinghe, B Chua, BW Day… - British journal of …, 2020 - nature.com
… biopsies that enable the detection of circulating biomarkers … non-invasive methods of
sampling to help in the diagnosis … 60 glioma patients, including 27 diagnosed with GBM, miRNA

Exosomal MicroRNA in Peripheral Serum as a Noninvasive Diagnostic Biomarker for Glioblastoma

A Semonche, AH Shah, ME Ivan, RJ Komotar - Neurosurgery, 2019 - journals.lww.com
sequencing (HTS), allows for the amplification, sequencing, and … Future prospective studies
testing the utility of exosome miRNA in … circulating exosomes hold promise as a diagnostic

Deep sequencing of small RNAs from neurosurgical extracellular vesicles substantiates miR-486-3p as a circulating biomarker that distinguishes glioblastoma from …

S Hallal, S Ebrahim Khani, H Wei, MYT Lee… - International journal of …, 2020 - mdpi.com
diagnosis with 91.7% accuracy [18]. A distinct, yet … 1480 miRNA species in CUSA-EVs captured
directly from gliomamakes it an attractive biomarker for monitoring of glioma progression …

Exosomal microRNA‑210 is a potentially noninvasive biomarker for the diagnosis and prognosis of glioma

F Lan, X Yue, T Xia - Oncology letters, 2020 - spandidos-publications.com
noninvasive potential biomarkers for the diagnosis and prognosis in various types of cancer.
The present study examined the diagnostic and prognostic value of serum exosomalglioma

Cell-free miRNAs as non-invasive biomarkers in brain tumors

O Beylerli, MJ Encarnacion Ramirez, A Shumadalova… - Diagnostics, 2023 - mdpi.com
… available non-invasive diagnostic techniques. The uncertainties surrounding … glioblastoma
[34]. This additional information provides insight into the possible origin of cell-free miRNAs, …

Novel molecular markers in glioblastoma—benefits of liquid biopsy

Z Birkó, B Nagy, Á Klekner, J Virga - International Journal of Molecular …, 2020 - mdpi.com
… or non-invasive diagnosis and monitoring cancer in humans. … group used a panel of seven
exosomal miRNAs—miR-182-… of GBM patients, due to the presence of the BBB, which makes

Significance of liquid biopsy in glioblastoma–A review

Á Klekner, L Szivos, J Virga, P Árkosy, L Bognár… - Journal of …, 2019 - Elsevier
… help to establish diagnosis in a non-invasive manner, and … of extracellular vesicles are the
exosomes, its nomenclature … of miRNA biomarkers in determination of glioma diagnosis in …

Exosomal circRNAs as promising liquid biopsy biomarkers for glioma

X Wu, M Shi, Y Lian, H Zhang - Frontiers in immunology, 2023 - frontiersin.org
… The present review provides an overview of the circulating … application of exosomal circRNAs
as tools to guide the diagnosis, … In addition, non-invasive liquid biopsy for the detection of …