Differences in circulating γδ T cells in patients with primary colon cancer and relation with prognostic factors

JC Andreu-Ballester, L Galindo-Regal… - PLoS …, 2020 - journals.plos.org
expression of γ, δ, ε and ζ chains in peripheral blood T cells of acute myeloid leukaemia …
all T cells, including αβ and γδ T cell subsets. In patients in whom a deficiency of γδ T cells was …

[HTML][HTML] Engineering γδ T cells: recognizing and activating on their own way

R Dong, Y Zhang, H Xiao, X Zeng - Frontiers in immunology, 2022 - frontiersin.org
… is deficient in human or mice, the development of αβ T cells … CD27 has been found to be
widely expressed in γδ T cells. It … against the HA-2-expressing CML and AML cells (142). In …

… spectroscopy-based identification of key pathways and genes enabling differentiation between acute myeloid leukemia and T cell acute lymphoblastic leukemia

H Liang, X Kong, Z Cao, H Wang, E Liu, F Sun… - Frontiers in …, 2023 - frontiersin.org
… , with PRKCQ-deficient mice exhibiting impaired T cell activation as a consequence of the
… , it can be seen that both T-ALL and AML patients have elevated albumin expression in their …

[HTML][HTML] Deep characterization of human γδ T cell subsets defines shared and lineage-specific traits

M Sanz, BT Mann, PL Ryan, A Bosque… - Frontiers in …, 2023 - frontiersin.org
… Next, we assessed whether PD-1 or TIGIT expression identified discrete cytotoxic γδ T cell
One key deficiency in our understanding of γδ T cell immunobiology is the lack of comparable …

Expanding and developing Vδ1 T lymphocytes as a cancer immunotherapeutic

GM Ferry - 2022 - discovery.ucl.ac.uk
… Vδ1 expression of T cell exhaustion markers following … Vδ1 expression of T cell exhaustion
markers following … as mice deficient in key signalling molecules lead to αβT cell differentiation …

Implications of T cell receptor biology on the development of new T cell therapies for cancer

IR Hardy, WW Schamel, PA Baeuerle, DR Getts… - …, 2020 - Future Medicine
… aberrant thymic cellularity and peripheral T cell deficiency [21]. … In contrast, 4-1BBζ CAR
T cells preferentially expressed T cell … Basic residues in the T-cell receptor zeta cytoplasmic …

[PDF][PDF] Targeting and Elimination of T Cell Subpopulations by Chimeric Antigen Receptor-modified T Cells

SN Petkova - 2021 - ediss.uni-goettingen.de
… of CAR-expressing T cells aimed at the elimination of B cells in … such as CD3 gamma (CD3γ),
delta (CD3δ) and epsilon (CD3ε) which are associated with a homodimer of two CD3 zeta (…

[图书][B] T-cell Checkpoint Pathways Modulate Cell Cycle and Steroid Resistance in T-cell Acute Lymphoblastic Leukaemia

Y Shi - 2020 - theses.ncl.ac.uk
zeta chain of T cell receptor associated protein kinase 70 … , which is only expressed in
immature T cells. Previous studies … -deficient mice, rather than Fyn-deficient mice, resulting in a T-…

CD38: T cell immuno-metabolic modulator

A Kar, S Mehrotra, S Chatterjee - Cells, 2020 - mdpi.com
… B cell-chronic lymphocytic leukemia, acute myeloid leukemia… Interestingly, PARP1 deficiency
in T cells tipped the balance … of the surface expression of the CD38 in CD4 T cells exhibited …

Notch partners in the long journey of T-ALL pathogenesis

ML Toribio, S González-García - International Journal of Molecular …, 2023 - mdpi.com
… of developing T cells during T-lymphopoiesis. Although … expression in normal T cells, MYC
is also broadly expressed … to that described for MYC-deficient T cells [184]. These results …