… of atherosclerosis compared to CD40-TRAF2/3/5 deficient mice. … In summary CD40L-CD40-TRAF6
signaling seems to be the … atherosclerosis was observed in leukocyte specific CD40-…

… part of the immune response in atherosclerosis is caused by … -deficient mice are characterized
by impaired leukocyte … Mice with a defective CD40-TRAF6 binding site also show reduced …

… phenotype of patients with genetic deficiency of these proteins, … leukocyte recruitment to the
plaque, reduced immune cell … inhibition of CD40-TRAF6 interactions prevents inflammation …

… mutation that prevented CD40–TRAF6 signaling. No beneficial … in atherosclerotic lesions in
apolipoprotein E deficient (ApoE … interaction inhibitor, resulting in dampened leukocyte rolling …

… CD40-TRAF6 inhibition attenuated atherosclerosis in … the atherosclerotic aorta, we
characterized changes in immune … Seven CD45+ leukocyte populations were identified by viSNE …

… The immune checkpoint protein CD40 is expressed on the … , and not CD40-TRAF 2,3,5
signalling, is involved in the … Atherosclerotic CD40-TRAF6 deficient mice display a polarization of …

… deficiency in specific CD40–TRAF interactions and found that the absence of CD40–TRAF6
but not CD40–TRAF2/3/5 signalling … are required to guide leucocytes from the circulation to …

… , macrophages, and T lymphocytes, particularly the binding of … as important signals for adaptive
immune responses and also … In addition, CD40 deficiency has been shown to reduce the …

… We also provide evidence that the CD40L–CD40–TRAF6 … of whole blood leukocytes, cardiac
RAGE signaling, vascular … shown that CD40L deficiency prevents all major complications …

… of atherosclerosis by preventing platelet-leukocyte aggregate … cell-specific CD40L deficiency
reduces atherosclerotic plaque … On the other hand, targeting CD40-TRAF6 signaling, which …