DNA methylation signatures reveal the diversity of processes remodeling hepatocellular carcinoma methylomes
… The DNA methylation landscape of human cancers is modulated by various factors, including
the cell of ori… Definition of the landscape of promoter DNA hypomethylation in liver cancer. …
the cell of ori… Definition of the landscape of promoter DNA hypomethylation in liver cancer. …
The landscape of DNA methylation in hepatocellular carcinoma
YF Zheng, X Lu, XY Zhang… - Journal of Cellular …, 2019 - Wiley Online Library
… and the change pattern of methylation status in the DNA promoter region of HCC samples …
Then, some DNA methylation genes that could accurately identify cancer and cancer-adjacent …
Then, some DNA methylation genes that could accurately identify cancer and cancer-adjacent …
DNA methylation profiling of human hepatocarcinogenesis
G Hernandez‐Meza, J von Felden… - …, 2021 - Wiley Online Library
… Figure 5A depicts the landscape of differential DNA methylation … (48) DNA hypermethylation
of promoter regions of tumor … DNA methylation profile of hepatocellular carcinoma and …
of promoter regions of tumor … DNA methylation profile of hepatocellular carcinoma and …
The DNA methylation landscape in cancer
… patterns, and indeed, developmental gene expression is often already repressed in
normal cells but these promoters are prone to abnormal DNA hypermethylation following …
normal cells but these promoters are prone to abnormal DNA hypermethylation following …
The mutational landscape of pancreatic and liver cancers, as represented by circulating tumor DNA
A Rice, A del Rio Hernandez - Frontiers in oncology, 2019 - frontiersin.org
… the mutational landscapes of both pancreatic and liver cancer, and … DNA methylation, in
addition to specific oncogenic methylations on promoter regions, can also be a marker for cancer…
addition to specific oncogenic methylations on promoter regions, can also be a marker for cancer…
The DNA methylation landscape of advanced prostate cancer
… liver biopsies were represented in these benign-adjacent samples, which exhibited distinct
methylation patterns from the tumor … We did not observe promoter hypermethylation of tumor …
methylation patterns from the tumor … We did not observe promoter hypermethylation of tumor …
Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming
… , focused on altered methylation at gene promoters and CpG … Given the well-established
inheritance mechanism of DNA methylation… The enhancer landscapes profiled in this study have …
inheritance mechanism of DNA methylation… The enhancer landscapes profiled in this study have …
Alternative promoters in CpG depleted regions are prevalently associated with epigenetic misregulation of liver cancer transcriptomes
C Nepal, JB Andersen - Nature Communications, 2023 - nature.com
… the reference promoter. We show that CG-poor regions preferentially lose DNA methylation
in tumor … To this end, we compared the DNA methylation landscapes of SETD2 mutated HCC …
in tumor … To this end, we compared the DNA methylation landscapes of SETD2 mutated HCC …
[HTML][HTML] DNA methylation biomarkers for diagnosis of primary liver cancer and distinguishing hepatocellular carcinoma from intrahepatic cholangiocarcinoma
Y Bai, W Tong, F Xie, L Zhu, H Wu, R Shi… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
… The methylator phenotype landscape of HCC and ICC. Heatmaps including … Through
differential methylation site analysis, we found that promoter regions were the most …
differential methylation site analysis, we found that promoter regions were the most …
[HTML][HTML] Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry
… Overall, this landscape has fueled the idea that two distinct age-related pathophysiological
… 200 and TSS 1500 promoter regions; in contrast, hypomethylated DMPs were rather spotted …
… 200 and TSS 1500 promoter regions; in contrast, hypomethylated DMPs were rather spotted …