Biomedical applications of the peptide decorated gold nanoparticles

A Rai, L Ferreira - Critical Reviews in Biotechnology, 2021 - Taylor & Francis
peptide-gold (Au) NP conjugates in the area of drug delivery, targeting, cancer therapy, brain
… of NPs and therefore prevent the conjugated peptide to be recognized by the cell receptors. …

Tumor targeting by peptide-decorated gold nanoparticles

B Albertini, V Mathieu, N Iraci… - Molecular …, 2019 - ACS Publications
… chemotherapeutic agents and drug-delivery systems that are able … is the conjugation of
doxorubicin with an RGD-like peptide (Doxo-… because of its ability to recognize the αvβ3 integrin. …

Nanoparticles for targeted brain drug delivery: what do we know?

RGR Pinheiro, AJ Coutinho, M Pinheiro… - International Journal of …, 2021 - mdpi.com
… in the brain, lectin conjugated nanoparticles are promising for … well recognized by the
transporters overexpressed in brain … and is testing the efficacy of gold nanocrystals in Parkinson’s …

Designing peptide nanoparticles for efficient brain delivery

A Duro-Castano, DM Leite, J Forth, Y Deng… - Advanced drug delivery …, 2020 - Elsevier
… However, shortcomings in our understanding of peptide self-assembly and blood–brain … in
engineering peptide nanocarriers for the delivery of therapeutic compounds to the brain: from …

Peptide mediated targeted delivery of gold nanoparticles into the demyelination site ameliorates myelin impairment and gliosis

S Farhangi, E Karimi, K Khajeh, S Hosseinkhani… - … , Biology and Medicine, 2023 - Elsevier
… solution to direct nanoparticles to the specific site by recognizing … We used ICP-MS to analyze
the amount of gold in the brain. … Peptide conjugation did not affect the morphology and the …

Peptide-conjugated ultrasmall gold nanoparticles (2 nm) for selective protein targeting

T Ruks, K Loza, M Heggen, O Prymak… - ACS Applied Bio …, 2021 - ACS Publications
… We have attached the following synthetic model peptides which contain the pTP recognition
… Of course, this variance has to be kept in mind when further calculations (like K D values or …

Surface modification of gold nanoparticles with neuron-targeted exosome for enhanced blood–brain barrier penetration

M Khongkow, T Yata, S Boonrungsiman… - Scientific reports, 2019 - nature.com
… provides a platform for conjugating multiple ligands (peptides, proteins, … nanoparticles for
targeted delivery to brain cells is limited partly due to the lack of targeting moieties recognized

Peptide-conjugated nano delivery systems for therapy and diagnosis of cancer

I Gaurav, X Wang, A Thakur, A Iyaswamy, S Thakur… - Pharmaceutics, 2021 - mdpi.com
… , targeting ability via recognizing biological receptors on cancer … charged or neutral peptides
on gold nanoparticles (AuNPs) … /background ratio in brain metastases compared with before …

[HTML][HTML] Gold-based nanomaterials for the treatment of brain cancer

L Tu, Z Luo, YL Wu, S Huo, XJ Liang - Cancer Biology & Medicine, 2021 - ncbi.nlm.nih.gov
… Importantly, biomolecule conjugation on NP surfaces endows … in brain tumors after epidermal
growth factor receptor peptidepeptide can efficiently cross the BBB and deliver therapeutic …

Biochemical assessment of the neurotoxicity of gold nanoparticles functionalized with colorectal cancer-targeting peptides in a rat model

MC Pereira, OB Adewale, S Roux… - Human & …, 2021 - journals.sagepub.com
… streptavidin and subsequent conjugation to biotinylated pC, … the sequence-independent
recognition of protein surfaces and … of gold nanoparticles in the different rat brain regions. Int J …