… its subsequent interaction with downstream adaptor protein MAVS, resulting in hindered
interferon … As explained above, DENV sfRNA targets innate immune signalling in human cells at …

… manipulate the innate immune responses of the host such as ‘… of RIG-I with the adaptor
protein MAVS by binding to the N-… The humoral immune system may also be directly subverted …

… Dengue virus (DENV) … host innate immune response. Herein, we examined the inhibitory
effects of DENV serotype 2 (DENV2) nonstructural proteins on RIG-I-directed antiviral immune …

… of MITA, thereby subverting the activation of downstream … ZIKV to escape the innate
immune response, providing new … dengue virus (DENV), hepatitis C virus, and West Nile virus, …

… or subvert autophagy process for escaping host immunity … TLRs recognize viral nucleic
acid, the adaptor proteins will be recruited … IFN-I signaling by targeting MAVS. The ATG5–ATG12 …

… signaling protein (MAVS) is a ubiquitous adaptor protein located … Innate immunity provides
the first line of defense against … the RIG-I/MAVS pathway and subverting innate and adaptive …

… regulation during Dengue virus, West Nile virus, Zika virus, … primary response 88 (MYD88)
adaptor protein (20, 26). MYD88 … According to reports, DENV NS4A binds to MAVS and blocks …

… viruses, including Dengue virus (DENV), West Nile virus (… in viral replication and
suppresses the RIG-I/MAVs pathway at … The interaction of polyubiquitinated RIG-I and MAVS is …

… human pathogens dengue virus (DENV), yellow fever virus (… oligomerization and its binding
to the adaptor protein MAVS [63,64]. … , ZIKV NS proteins were shown to inhibit innate immune …

… through interaction with adaptor proteins, triggering expression … system (RIG-I/MAVS
pathway being the main cytosolic RNA … Dengue virus (DENV) is transmitted by Aedes aegypti …