[HTML][HTML] Coordinated bi-directional trafficking of synaptic vesicle and active zone proteins in peripheral nerves

JK Juranek, K Mukherjee, R Jahn, JY Li - Biochemical and Biophysical …, 2021 - Elsevier
… First, we followed the transport of an integral synaptic vesicle … PTVs diminishes indicating
that other mechanisms of AZ protein … We did not find any dense core vesicles in our electron …

[HTML][HTML] Rab2 drives axonal transport of dense core vesicles and lysosomal organelles

VK Lund, MD Lycas, A Schack, RC Andersen, U Gether… - Cell Reports, 2021 - cell.com
After synthesis in the endoplasmic reticulum (ER) and transit … and lysosome-related active-zone
transport vesicles. We also … normally fed larvae was substantially reduced (to one third or …

The synaptic vesicle cycle revisited: new insights into the modes and mechanisms

NL Chanaday, MA Cousin, I Milosevic… - Journal of …, 2019 - Soc Neuroscience
… resting pool and fuse at the active zone, after which they may be … zone can retrieve
endocytic vesicles that rapidly fuse with … A recent study suggested that SV clusters represent an …

Ultrastructural distribution of presynaptic active zones and dense core vesicles in olfactory projection neurons of Drosophila

K Yang, H Liu, Z Di, A Guo, K Zhang - bioRxiv, 2021 - biorxiv.org
… 8.4 μm 2 and 119.5 μm 2 (mean 43.5 μm 2 ), the volume of … In the current study, after
determining all the aforementioned … animals may compensate for reduced synapse release …

[HTML][HTML] An overview of the synaptic vesicle lipid composition

B Binotti, R Jahn, Á Pérez-Lara - Archives of Biochemistry and Biophysics, 2021 - Elsevier
… The new SVs filled with neurotransmitter remain and dock at the active zone (3). After fusion,
the … Question marks mean processes not well characterized.(created with BioRender.com ). …

[HTML][HTML] Hypothesis Relating the Structure, Biochemistry and Function of Active Zone Material Macromolecules at a Neuromuscular Junction

JA Szule - Frontiers in Synaptic Neuroscience, 2022 - frontiersin.org
… SVs to the active zone, SV docking as a directed approach to the PM, SV priming after it
has … of the authors and do not necessarily represent those of their affiliated organizations, or …

[HTML][HTML] Synaptic vesicles having large contact areas with the presynaptic membrane are preferentially hemifused at active zones of frog neuromuscular junctions …

JH Jung - International Journal of Molecular Sciences, 2019 - mdpi.com
… hemifused synaptic vesicles (660 nm 2 ± 150 nm 2 , mean ± … hemifusion of synaptic vesicles
occurs after a nerve impulse … of synaptic vesicles at the active zone and the synaptic vesicles

Direct observation of vesicle transport on the synaptic ribbon provides evidence that vesicles are mobilized and prepared rapidly for release

C Joselevitch, D Zenisek - Journal of Neuroscience, 2020 - Soc Neuroscience
… the mean fluorescence and SEM of a sample of 30 vesicles … by vesicles moving from outside
of our evanescent field after … in a decreased release probability of these captured vesicles

Presynaptic development is controlled by the core active zone proteins CAST/ELKS

T Radulovic, W Dong, RO Goral… - The Journal of …, 2020 - Wiley Online Library
… Forty-eight hours after infection, after cytopathic effects have … that at P7 ELKS levels were
severely reduced in Cast −/− Elks −… vesicles as a function of their distance to AZ (left), and mean

[PDF][PDF] DISSECTING THE LEVEL OF EXPRESSION AND CLUSTERING OF ACTIVE ZONE PROTEINS AT DOPAMINE AND ACETYLCHOLINE RELEASE TERMINALS

P Nemcová - 2019 - marshallplan.at
… TH+ synaptosomes that do not contain any B represent the level of POI at DA axons. POI in
B… Detected level of postsynaptic density followed the level of active zone proteins accounting …