… or enhance perceived pain via descending inhibitions or … circuitry that drives the full pain
experience. But while results … of the descending modulation of pain perception has never been …

… This study describes an ascending–descending pain modulation pathway triggered by
pain and dependent on the NAc and on the PAG–RVM descending system. The ascending …

… demonstrates conclusively that descending controls modulate nociceptive information
contributing to the affective aspect of pain, and also differentiates descending modulation from that …

… The papers regarding other descending pain modulation pathways (serotonin- and …
descending pain modulation is mainly mediated by monoaminergic pathways, including descending …

… pain behaviors by reducing descending noradrenergic and serotoninergic modulation of spinal
pain … Thus, a long-range brain circuit was identified that is crucial for pain processing and …

… The descending control modulates pain circuitry at multiple levels, … of descending pain
modulation favoring pain facilitation contributes to the promotion and maintenance of chronic pain …

… Overall, our results provided evidence suggesting deficits in ascending and descending
pain modulation pathways, which were highly associated with the intensity of chronic pain and …

… controls link higher processing of noxious signals to modulation of spinal cord responses
to their noxious inputs. It has become possible to study one key inhibitory system in animals …

… assessing descending pain modulation in humans and animals are conditioned pain modulation
(… In CPM paradigms, this “pain-inhibits-pain” effect is assessed via the modulation of the …

… of neuropathic pain on the brain opioidergic system remain understudied. Since descending
facilitation is enhanced during neuropathic pain, we studied the opioidergic modulation of …