Design of self-dispersible microsponge containing cyclosporine through wet milling and drop freeze-drying processes to improve dissolution behavior

M Kobayashi, K Kondo, C Nakashima, Y Kida… - Journal of Drug Delivery …, 2020 - Elsevier
spray freeze-drying (SFD) method combined with wet-milling … the milled nanosuspension
dropwise from a nozzle tip into liquid … tool improving the solubility of poorly water-soluble drugs. …

… : Physicochemical characterization and stability assessment of self-dispersible Atorvastatin/Tween 80® nanocrystals formulated through wet milling and freeze-drying

A Rossetti, DA Real, BA Barrientos… - International Journal of …, 2024 - Elsevier
… with Tween 80® were designed by wet milling. A full factorial … with different cryoprotectants
was carried out to obtain a dry … the nanocrystals as a nanosuspension and would be slowed …

Design of xerogel pill with good swallowing performance through wet milling and drop freeze-drying processes

R Asai, T Takeuchi, K Kondo, T Niwa - International Journal of …, 2022 - Elsevier
… The spray freeze-drying (SFD) technique has been previously established to … poorly
water-soluble drugs in our laboratory. A drug nanosuspension prepared through a wet-beads milling

Spray freeze drying to solidify Nanosuspension of Cefixime into inhalable microparticles

DM Haghighi, H Faghihi, M Darabi… - DARU Journal of …, 2022 - Springer
Design of self-dispersible dry nanosuspension through wet milling and spray freeze-drying
for poorly water-soluble drugs. Eur J Pharm Sci : Off J Eur Fed Pharm Sci. 2013;50(3–4):272–…

Formulation of ketoconazole nanocrystal-based cryopellets

A Touzet, F Pfefferlé, A Lamprecht, Y Pellequer - AAPS PharmSciTech, 2020 - Springer
… by alternative methods like spray freeze drying (23), the … was chosen as a poorly water-soluble/hydrophobic
model drug in this … into the starting nanosuspensions after their production by …

[HTML][HTML] A combined isolation and formulation approach to convert nanomilled suspensions into high drug-loaded composite particles that readily reconstitute

A Coelho, L Schenck, G Guner, A Punia, E Bilgili - Powders, 2022 - mdpi.com
… for converting wet media milled nanosuspensions into high drug-… are categorized as poorly
water-soluble, which originates … –surfactants) were wet milled in a stirred media mill. The …

[HTML][HTML] Improvement of drug delivery properties of risperidone via preparation of fast dissolution tablet containing nanostructured microparticles

M Salarvand, V Ramezani, F Salarvand… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
… the compliance of psychotic patients, we designed a fast dissolution tablet (FDT) … Spray
freeze-drying of nanosuspension Aqueous nanosuspension was dried with spray freeze-drying

[PDF][PDF] Development of Cyclosporine A Nanosuspension using Experimental Design by Response Surface Methodology: In Vitro Evaluations

SG Pınar, N Çelebi - 2023 - cms.turkjps.org
Design of self-dispersible microsponge containing cyclosporine through wet milling and
drop freeze-dryingspray granulation for conversion of a nanosuspension into a …

Itraconazole nanocomposites prepared via rotary evaporator drying of nanomilled suspensions

AS Coelho - 2021 - digitalcommons.njit.edu
… bed coating, freeze drying, and spray drying, respectively (… all explored as water-soluble
polymers to aid in processing of … drug nanocomposites, using the drug nanosuspensions as …

Ricobendazole nanocrystals obtained by media milling and spray drying: pharmacokinetic comparison with the micronized form of the drug

AJ Paredes, NM Camacho, L Schofs, A Dib… - International Journal of …, 2020 - Elsevier
Drug nanosuspensions (NSs) can be produced by both, the … three different treatments using
a 3x3 crossover design. Each … of poorly water-soluble drugs during wet stirred media milling