[HTML][HTML] From DNA human sequence to the chromatin higher order organisation and its biological meaning: using biomolecular interaction networks to understand the …
… a significant functional impact on gene expression. The high-… mediated by the CTCF protein
detected in a ChIA-PET … on the genome's mesoscale network structure. They also explain …
detected in a ChIA-PET … on the genome's mesoscale network structure. They also explain …
[HTML][HTML] Protein complex prediction: A survey
… In this article, most important computational methods for protein … ontology annotations and
gene expression profiles with those … information and/or network structure to detect conserved …
gene expression profiles with those … information and/or network structure to detect conserved …
[HTML][HTML] A comparative study of cluster detection algorithms in protein–protein interaction for drug target discovery and drug repurposing
J Ma, J Wang, LS Ghoraie, X Men… - Frontiers in …, 2019 - frontiersin.org
… data, we first accessed the normalized gene expression in the … entire network topology
propriety and perturbation data to … genes that participate big functional clusters are important for …
propriety and perturbation data to … genes that participate big functional clusters are important for …
Integrated network analysis and machine learning approach for the identification of key genes of triple‐negative breast cancer
LD Naorem, M Muthaiyan… - Journal of cellular …, 2019 - Wiley Online Library
… integration of various gene expression data sets. Additionally… This package detects outlier
samples based on three quality … parameters that describe the network topology such as degree …
samples based on three quality … parameters that describe the network topology such as degree …
Integration of multiomics data with graph convolutional networks to identify new cancer genes and their associated molecular mechanisms
… type of data—either multiomics features or the network topology. … data, we found that the
sensitivity of EMOGI in detecting KCGs … , DNA methylation and gene expression data of 29,446 …
sensitivity of EMOGI in detecting KCGs … , DNA methylation and gene expression data of 29,446 …
Network-based identification genetic effect of SARS-CoV-2 infections to Idiopathic pulmonary fibrosis (IPF) patients
… GEO database was introduced for gene expression analysis … it contains 11 methods for
topological analysis [38]. The hub … of this study including hub gene detection for identifying drug …
topological analysis [38]. The hub … of this study including hub gene detection for identifying drug …
[HTML][HTML] Detection of molecular signatures and pathways shared in inflammatory bowel disease and colorectal cancer: a bioinformatics and systems biology approach
… Also, we have identified crucial pathways, hub proteins, and … from JASPAR database based
on topological analysis using … We analyzed the gene expression microarray data from NCBI…
on topological analysis using … We analyzed the gene expression microarray data from NCBI…
[HTML][HTML] Comparative analyses of gene co-expression networks: Implementations and applications in the study of evolution
… The increasing abundance of gene expression data makes GCNs … Differential co-expression
analysis also detects differences … evolution, comparing network structure without relying on …
analysis also detects differences … evolution, comparing network structure without relying on …
Integrated bioinformatics analysis of expression and gene regulation network of COL12A1 in colorectal cancer
Y Wu, Y Xu - Cancer medicine, 2020 - Wiley Online Library
… genetic alterations correlated with tumorigenesis and progression is essential for identifying
new … .26, 27 Alterations of COL12A1 gene in chromosomal structure can cause its aberrant …
new … .26, 27 Alterations of COL12A1 gene in chromosomal structure can cause its aberrant …
[HTML][HTML] A linear regression and deep learning approach for detecting reliable genetic alterations in cancer using dna methylation and gene expression data
… We provided detail hub gene network structure in a Supplementary File, Additional file 7: …
hub genes detected by our method played an important role in the respective cancer. PAIP 2 …
hub genes detected by our method played an important role in the respective cancer. PAIP 2 …