Prophylactic mastectomy and occult malignancy: Surgical and imaging considerations

JL Thompson, BR Sinco, RL McCaffrey… - Journal of Surgical …, 2023 - Wiley Online Library
… The ability to reliably identify sentinel nodes following mastectomy is impeded by disrupted
cancer detection and the time lapsed from preoperative MRI to surgery. While breast MRI is …

Incidence of Occult Breast Cancer in Carriers of BRCA1/2 or Other High-Penetrance Pathogenic Variants Undergoing Prophylactic Mastectomy: When is Sentinel …

SM Wong, A Ferroum, C Apostolova… - Annals of Surgical …, 2022 - Springer
… In the subgroup of women who underwent preoperative MRI and had occult malignancy, 80…
This resulted in an overall MRI sensitivity of 78% for detection of occult cancer. Furthermore, …

Is sentinel lymph node biopsy necessary in patients who undergo prophylactic mastectomy?

V Madan, EP Mamounas - Clinical Breast Cancer, 2023 - Elsevier
… This study also suggests that use of preoperative breast MRI imaging could offer a potential
non-invasive tool to detect occult malignancy and select patients who can safely undergo …

Utility and outcomes of preoperative screening breast MRI for planned bilateral prophylactic mastectomy in high-risk patients

AS Taliaferro, ER Price, JH Hayward… - American Journal of …, 2022 - Am Roentgen Ray Soc
… suggest that preoperative breast MRI may be useful for detecting clinically occult malignancy
in … Given the high NPV of breast MRI, our results indicate that sentinel node biopsy may be …

Incidence of Cancer and Role of Sentinel Lymph Node Biopsy in BRCA Mutation Carriers Undergoing Prophylactic Mastectomies

SC Fat, C Weed, Y Samaha, A Chung… - The American …, 2023 - journals.sagepub.com
… with occult malignancy, this study evaluated the use of … these findings as MRI failed to detect
8 of 10 malignancies. … for patients with preoperative imaging that detected malignancies, as …

The association of preoperative magnetic resonance imaging (MRI) with surgical management in patients with early-stage breast cancer

PA Borowsky, S Choi, JF Moore, A White… - Journal of Surgical …, 2022 - Elsevier
… , locating primary breast tumors in patients with occult cancer, and … mastectomy and
contralateral prophylactic mastectomy (CPM… The authors found that preoperative MRI detected an …

Comparison of Clinical Breast Exam to Breast MRI Surveillance in Patients Following Nipple-Sparing Mastectomy

C Weed, T Wang, SC Mohan, X Wang, J Tseng… - … Breast Cancer, 2024 - Elsevier
… in preoperative T stage between patients who had MRI … of utmost clinical utility in detecting
LRR compared to MRI-based … lower detection rates of clinically occult, non-palpable cancer

Delayed sentinel lymph node dissection in patients with a preoperative diagnosis of ductal cancer in situ by preoperative injection with superparamagnetic iron oxide …

A Karakatsanis, S Eriksson, L Pistiolis… - Annals of Surgical …, 2023 - Springer
… Difficulty in preoperatively assessing the risk for occultPreoperative magnetic resonance
imaging (MRI) has not been … in detecting a lymph node, it was likely not the sentinel lymph …

[PDF][PDF] Preoperative breast magnetic resonance imaging

A Eisen, GG Fletcher, S Fienberg… - … in Evidence-Based …, 2021 - cancercareontario.ca
… breast cancer diagnosis but before surgery to detect additional … MRI may detect
mammographically occult tumours in the … , and thus possibly avoid sentinel lymph node biopsy or …

[HTML][HTML] De-escalating axillary surgery in early-stage breast cancer

EH Hersh, TA King - The Breast, 2022 - Elsevier
… ; moving away from axillary node dissection to sentinel lymph node biopsy (SLNB) and now
… Among those with a preoperative MRI, the sensitivity of MRI for detecting otherwise occult