[HTML][HTML] Potentiation of Brain-Derived Neurotrophic Factor-Induced Protection of Spiral Ganglion Neurons by C3 Exoenzyme/Rho Inhibitor

J Harre, L Heinkele, M Steffens, A Warnecke… - Frontiers in Cellular …, 2021 - frontiersin.org
… additional western blot experiments to detect ADP-ribosylated RhoA in cell lysates of the
in vitro cultured SGN. When C3 is taken up by cells, it ADP-ribosylated the RhoA protein and …

[HTML][HTML] Clostridium botulinum C3bot mediated effects on cytokine-induced psoriasis-like phenotype in full-thickness skin model

A Rohrbeck, VA Bruhn, N Hussein… - Naunyn-schmiedeberg's …, 2024 - Springer
… α-zonula occludens-1 mouse monoclonal antibody (1:100 in 5… e) was chosen for the
quantification of the mean fluorescence … ADP-ribosylated RhoA was detected by a specific …

Down-regulation of rho GTPase-activating protein 7 (DLC1) in tear film and modulation of rho GTPase dynamics by Rosuvastatin in dogs suffering from …

CR Swapana, A Gopinathan, K Singh… - Journal of Animal …, 2020 - indianjournals.com
Rho GTPases activity in tear fluid as well as ocular surface epithelium (OSEC) during
progression of Keratoconjunctivitis sicca (KCS) and their modulation with Rosuvastatin in dogs …

[HTML][HTML] From signal transduction to protein toxins—a narrative review about milestones on the research route of C. difficile toxins

K Aktories - Naunyn-Schmiedeberg's Archives of Pharmacology, 2023 - Springer
Quantification and statistics of the experiment given under B. … The best characterized
protein substrates of TcdB are RhoA/B… Here, CDTa ADP-ribosylated G-actin and inhibits the …

Domperidone protects mammalian cells from protein toxins of Bordetella pertussis, Clostridium botulinum, and Clostridioides difficile

J Jia - 2024 - oparu.uni-ulm.de
… cells with Rad or CsA reduced the ADP-ribosylated Gαi. In fluorescence … The anti-TcdB
monoclonal antibody bezolotoxumab has … The intensity of Western blot signals was quantified by …

Targeting the Toxin B glucosyltransferase domain of NAP1/B1/027 Clostridioides difficile using an attenuated Salmonella enterica Typhimurium vaccine vector

P Upadhyaya - 2022 - search.proquest.com
Clostridioides difficile (C. difficile) is the most common cause of nosocomial antibiotic-associated
diarrhea in developed countries and is classified as an urgent threat by the Centers of …

Charakterisierung der Wirkung bakterieller Proteintoxine auf humane neutrophile Granulozyten

S Schreiner - 2022 - oparu.uni-ulm.de
In der vorliegenden Arbeit wurde die Wirkung bakterieller Proteintoxine auf humane
neutrophile Granulozyten untersucht. Dabei wurde mit den clostridialen Toxinen C2 und C3 …