[HTML][HTML] MICAL2 is expressed in cancer associated neo-angiogenic capillary endothelia and it is required for endothelial cell viability, motility and VEGF response

I Barravecchia, S Mariotti, A Pucci, F Scebba… - … et Biophysica Acta (BBA …, 2019 - Elsevier
… of the anti-angiogenic approach is to stabilize tumor growth … -angiogenesis, we turned to a
pathophysiological model of … in this physical interaction, however our gene expression study

Emerging applications of anti-angiogenic nanomaterials in oncotherapy

B Tang, W Ma, Y Lin - Journal of Controlled Release, 2023 - Elsevier
Anti-angiogenic drugs target angiogenesis signaling … growth factor (bFGF) and prevent
the proliferation of human umbilical vein endothelial cells (HUVECs), showing an anti-angiogenic

[HTML][HTML] Synthesis, anti-angiogenic activity and prediction toxicity of (E)-3-(3-methoxyphenyl) propenoic acid

J Ekowati, KA Nofianti, MN Yunita… - Journal of Public …, 2023 - ncbi.nlm.nih.gov
… Anti angogenic activity was showed by endothelial cells growth … The energy minimization of
the 3D molecular structure was … endothelial cells, while one of the phases of angiogenesis is …

Angiopoietin inhibitors: A review on targeting tumor angiogenesis

D Parmar, M Apte - European journal of pharmacology, 2021 - Elsevier
… This article focuses on angiopoietins as alternative and potential targets for anti angiogenic
… sprouts develop from existing capillaries. The dormant endothelial cells initiate angiogenesis

Enhanced penetration of pro-apoptotic and anti-angiogenic micellar nanoprobe in 3D multicellular spheroids for chemophototherapy

A Mozhi, V Sunil, W Zhan, PB Ghode, NV Thakor… - Journal of controlled …, 2020 - Elsevier
… results in animal models, we developed 3D multicellular tumour … only endothelial cells and
the treated endothelial cells led us to … Angiogenesis assay on HUVEC cells: a) Phase contrast …

Tumor development and angiogenesis in adult brain tumor: glioblastoma

BK Ahir, HH Engelhard, SS Lakka - Molecular neurobiology, 2020 - Springer
… as cells (endothelial cells and mural cells), soluble growth factors, … All these different molecular
effectors interact using various … and exerts anti-angiogenic and anti-cancer activity [89]. A …

Recapitulating the angiogenic switch in a hydrogel-based 3D in vitro tumor-stroma model

C Kuehlbach, S Hensler, MM Mueller - Bioengineering, 2021 - mdpi.com
… To inhibit tumor growth by developing efficient anti-angiogenic … initiating angiogenesis is
essential. Yet so far, predominantly 2D … by endothelial cells and vessel associated cells, tumor

Ets-1 drives breast cancer cell angiogenic potential and interactions between breast cancer and endothelial cells

A Furlan, C Vercamer, L Heliot… - International …, 2019 - spandidos-publications.com
… -1 overexpression in cancer cells promotes angiogenesis by … Anti-angiogenic agents have
thus emerged as promising … , primitive endothelial cells can control the developing endoderm (…

Angiogenesis-on-a-chip coupled with single-cell RNA sequencing reveals spatially differential activations of autophagy along angiogenic sprouts

S Lee, H Kim, BS Kim, S Chae, S Jung, JS Lee… - Nature …, 2024 - nature.com
… Here, we apply an angiogenesis-on-a-chip to reconstruct 3D … -cell RNA sequencing of
sprouting endothelial cells from our … developing autophagy-based anti-angiogenic therapeutics. …

Tumor spheroid-on-a-chip: A standardized microfluidic culture platform for investigating tumor angiogenesis

J Ko, J Ahn, S Kim, Y Lee, J Lee, D Park, NL Jeon - Lab on a Chip, 2019 - pubs.rsc.org
… , we developed 3D perfusable blood vessel network and tumor … In our tumor angiogenesis
experiments, endothelial cells were … the effect of representative anti-angiogenic cancer drugs, …