[HTML][HTML] Proof of concept for a single-dose Group B Streptococcus vaccine based on capsular polysaccharide conjugated to Qβ virus-like particles

F Carboni, R Cozzi, G Romagnoli, G Tuscano… - npj Vaccines, 2023 - nature.com
… pre-immune titers above the Limit of Quantification (LOQ), and … Antibody responses in these
unprimed subjects could not be … We investigated the possibility to develop a GBS vaccine for …

[HTML][HTML] An acute rheumatic fever immune signature comprising inflammatory markers, IgG3, and Streptococcus pyogenes-specific antibodies

N Lorenz, R McGregor, AL Whitcombe, P Sharma… - Iscience, 2024 - cell.com
Quantification of GAS-specific antibody responses revealed that subclass polarization was …
-protein responses polarized to IgG3 in all groups. However, the magnitude of responses was …

Antibody responses to respiratory syncytial virus: a cross-sectional serosurveillance study in the Dutch population focusing on infants younger than 2 years

G Berbers, L Mollema, F van der Klis… - The Journal of …, 2021 - academic.oup.com
… , we developed a high-throughput pentaplex immunoassay … than 10 years for this analysis,
we additionally attempted to … -specific antibodies throughout life using a sensitive multiplex

[HTML][HTML] Should pneumococcal serotype 3 be included in serotype-specific immunoassays?

E Linley, A Bell, JF Gritzfeld, R Borrow - Vaccines, 2019 - mdpi.com
… evaluate antibody levels, multiplex immunoassays have been … a booster dose did not elicit
an increased antibody response. … analysis performed, are on the UK NEQAS IIA website [34]. …

Point‐of‐critical‐care diagnostics for sepsis enabled by multiplexed micro and nano sensing technologies

BK Ashley, U Hassan - Wiley Interdisciplinary Reviews …, 2021 - Wiley Online Library
… For example, fluorescence quantification has been developed and characterized for decades
as an accurate tool for measuring cell surface receptors, soluble proteins, and pathogens. …

[HTML][HTML] Standardized whole blood assay and bead-based cytokine profiling reveal commonalities and diversity of the response to bacteria and TLR ligands in cattle

J Lesueur, S Walachowski, S Barbey… - Frontiers in …, 2022 - frontiersin.org
… Recent developments in multiplex technologies enable the … a large group of cattle. Here,
we show that the bead-based multiplex assay combined with a multivariate analysis allows the …

… assays detecting antibodies against Corynebacterium diphtheriae and Clostridium tetani toxins, rubella virus and parvovirus B19 for incorporation into Multiplex …

N Brenner, J Butt, IL Bomfim, J Tabatabai, M Pawlita… - Methods, 2019 - Elsevier
… Here, we report the development and validation of Monoplex … Quantitative comparison of
rubella antibody reactivities in … Antibody responses to VP2 and NS1 were less strong with a …

The development of immunological assays to evaluate the level and function of antibodies induced by Klebsiella pneumoniae O-antigen vaccines

HR Wagstaffe, M Johnson, G Osman, P Martin… - Msphere, 2023 - Am Soc Microbiol
… a Luminex-based multiplex antibody binding assay and both … The lower limit of quantification
(LLOQ) was determined as 4 … from the validated Streptococcus pneumoniae OPA which …

[HTML][HTML] … assay for testing potency of combination DTaP vaccines: Simultaneous quantitation of anti-DT, anti-TT, anti-PTxd and anti-FHA antibodies in Guinea-pig …

S Bandiera, A Lebas, L Canizares-Martinello… - Biologicals, 2019 - Elsevier
… xMAP®-bead-based multiplex immunoassay for estimating the … immune responses to a
13-valent streptococcus pneumonia … During the development of this multiplex Luminex SIA assay …

Microfluidic devices for multiplexed detection of foodborne pathogens

X Han, Y Liu, J Yin, M Yue, Y Mu - Food Research International, 2021 - Elsevier
… is developed to simplify the procedure and integrated with detection chip to form an enclosed
system performing “sample-in to answer-out” analysis. The … The fluorescent signal could be …