… Thus, it may serve as a potential therapeutic agent in the treatment of metabolic disorders
[45]. Gut microbiota also play a crucial role in lipid metabolism because of their ability to …

… cancer, cardiovascular and cerebrovascular diseases as well … function changes, poly
ADP-ribose polymerase 1 (PARP1) is … NAD + to cause mitochondrial dysfunction (144). …

… cerebral ischemia, leading to severe clinical manifestations such as heart failure, myocardial
infarction (MI), cerebral … inhibiting the activation of poly (ADP-ribose) polymerase 1 (PARP-1…

… to the activation of caspase9 and poly (ADP-ribose) polymerase (PARP), which leads to …
As a result, β-islet cells in animal models of obesity and type 2 diabetes induced by a high …

… 3-P dehydrogenase by poly-ADP-ribose polymerase 1 and the resultant buildup of the …
(Malvaceae) leaf extract attenuates diabetes induced nephropathy and cardiomyopathy via …

… of diabetes-induced hypertension and abrogated diabetes-induced vasoconstriction [47]. …
of NO as well as prevented the overactivation of poly ADP-ribose polymerase-1 (Table 2) [131]. …

… , upregulation of poly ADP-ribose polymerase (PARP), and … rats subjected to permanent
middle cerebral artery occlusion (… can prevent diabetes-induced vascular dysfunction in the reti…

… effects against diabetes-induced damage by restoring vascular endothelial function [12]. …
cleaved poly (ADP-ribose) polymerase (PARP), which serves as a marker for apoptosis [97]. …

… rhiza for cardiovascular and cerebrovascular diseases, with 10 … that poly ADP-ribose
polymerase (PARP) plays key roles in … type 2 diabetes induced by high-fat diet and streptozotocin. …

… a contributing factor to diabetes-induced nerve dysfunction [44]. … and activation of poly(ADP-ribose)
polymerase while improving … diabetes-induced vascular and neural dysfunction than …