[HTML][HTML] Dietary fructose as a model to explore the influence of peripheral metabolism on brain function and plasticity

F Gomez-Pinilla, RP Cipolat, LFF Royes - Biochimica et Biophysica Acta …, 2021 - Elsevier
… that fructose consumption aggravates the effects of brain trauma on molecular systems
engaged in cell energy … organs and systems that contribute to brain pathology. These actions of …

[HTML][HTML] Western diet aggravates neuronal insult in post-traumatic brain injury: proposed pathways for interplay

A Shaito, H Hasan, KJ Habashy, W Fakih… - …, 2020 - thelancet.com
… , including diet, constitute additional risk affecting TBI consequences and … diet (WD) intake
and TBI pathophysiology. As such, poor … The brain is an energy-intensive organ that can utilize …

[HTML][HTML] Fructose removal from the diet reverses inflammation, mitochondrial dysfunction, and oxidative stress in hippocampus

A Mazzoli, MS Spagnuolo, M Nazzaro, C Gatto, S Iossa… - Antioxidants, 2021 - mdpi.com
… Several studies have revealed that dietary fructose can increase brain expression of the
fructose transporter Glut-5 [17,48] and sugar metabolism [49,50,51]. In this study, we showed …

[HTML][HTML] Sweet but bitter: Focus on fructose impact on brain function in rodent models

MS Spagnuolo, S Iossa, L Cigliano - Nutrients, 2020 - mdpi.com
Fructose influence on synaptic plasticity and cognition, with a … of a high fructose diet (55%
of energy from fructose) throughout … Dietary fructose is absorbed across the small intestine …

[HTML][HTML] Glucose metabolism: A link between traumatic brain injury and Alzheimer's disease

XJ Xu, MS Yang, B Zhang, F Niu, JQ Dong… - Chinese journal of …, 2021 - Elsevier
pathology in both TBI and AD. On the one hand, TBI perturbs the glucose metabolism of the
brain, and causes energy … perturbation would influence cerebral glucose metabolism, which …

[HTML][HTML] Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury

J Nwaiwu, S Ibeh, MA Reslan, NMZ Bakkar… - Journal of …, 2024 - Elsevier
… In TBI pathology, mitochondrial dysfunction results in energy depletion and inadequate …
fed a high-fat high fructose diet demonstrated the influence of chronic inflammatory peripheral …

High concentrations of fructose cause brain damage in mice

A Cargnin-Carvalho, MR da Silva… - … and Cell Biology, 2023 - cdnsciencepub.com
… consumption causes resistance to leptin, an increase in leptin levels without affecting fat …
This study showed that fructose intake 20%, associated with a high-fat diet, is a determining …

Making sense of gut feelings in the traumatic brain injury pathogenesis

LFF Royes, F Gomez-Pinilla - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
… the TBI pathology have been centered on the brain, and we … between mechanisms that
regulate energy metabolism and … have the potential to influence the production of inflammatory …

Progress in research on the role of clinical nutrition in treating traumatic brain injury affecting the neurovascular unit

JQ Lai, XR Chen, S Lin, CN Chen… - Nutrition Reviews, 2023 - academic.oup.com
… Poor dietary habits may worsen the pathology and prognosis … fructose intake can disturb
brain metabolism by affecting … of ketogenic diets may be associated with energy metabolism, …

[HTML][HTML] Liver acts as a metabolic gate for the traumatic brain injury pathology: Protective action of thyroid hormone

M Khandelwal, G Krishna, Z Ying… - Biochimica et Biophysica …, 2023 - Elsevier
… which traumatic brain injury (TBI) and dietary fructose influence liver … that can be used as
energy source. Additionally, since … of fructose that was further aggravated by TBI pathogenesis. …