Pain inhibits pain: an ascending-descending pain modulation pathway linking mesolimbic and classical descending mechanisms
G Tobaldini, NF Sardi, VA Guilhen, L Fischer - Molecular neurobiology, 2019 - Springer
… detected in a standard rat model of inflammatory pain (hindpaw injection of carrageenan)…
mechanisms underlying their pain inhibitory descending activity, these findings provide the first …
mechanisms underlying their pain inhibitory descending activity, these findings provide the first …
Neuroimmune modulation of pain across the developmental spectrum
… of the mechanisms involved in pain sensitization and … neonatal inflammation and programming
of pain responsiveness later in life… The pattern overlaps with several known intrinsic brain …
of pain responsiveness later in life… The pattern overlaps with several known intrinsic brain …
COVID-pain: acute and late-onset painful clinical manifestations in COVID-19–molecular mechanisms and research perspectives
M Cascella, A Del Gaudio, A Vittori… - Journal of Pain …, 2021 - Taylor & Francis
… they infiltrate the DRG during inflammatory pain, and the … /CD200R inhibitory axis could
attenuate many of the inflammatory … override the intrinsic ability of the virus to damage the CNS. …
attenuate many of the inflammatory … override the intrinsic ability of the virus to damage the CNS. …
Understanding the molecular mechanisms underlying the pathogenesis of arthritis pain using animal models
JI Hong, IY Park, HA Kim - International Journal of Molecular Sciences, 2020 - mdpi.com
… lagged behind other areas, such as inflammation control and … analgesic mechanisms mediating
endogenous pain inhibitory … the lumbar dorsal root ganglia during the late phase, further …
endogenous pain inhibitory … the lumbar dorsal root ganglia during the late phase, further …
Activation of the intrinsic pain inhibitory circuit from the midcingulate Cg2 to zona incerta alleviates neuropathic pain
TT Hu, RR Wang, Y Du, F Guo, YX Wu… - Journal of …, 2019 - Soc Neuroscience
… , the underlying mechanisms are still not fully understood. … at the same site and mice were
killed another week later. … contralateral inflammatory pain and had no effect on thermal pain. …
killed another week later. … contralateral inflammatory pain and had no effect on thermal pain. …
[HTML][HTML] Mechanisms of peripheral and central pain sensitization: focus on ocular pain
G Puja, B Sonkodi, R Bardoni - Frontiers in Pharmacology, 2021 - frontiersin.org
… in neuropathic pain and decreased during inflammation. … transmission at Sp5 and the intrinsic
properties of neurons receiving … inhibitory system may be critical also in chronic eye pain. …
properties of neurons receiving … inhibitory system may be critical also in chronic eye pain. …
[PDF][PDF] Spontaneous pain disrupts ventral hippocampal CA1-infralimbic cortex connectivity and modulates pain progression in rats with peripheral inflammation
L Ma, L Yue, Y Zhang, Y Wang, B Han, S Cui, FY Liu… - Cell reports, 2019 - cell.com
… of circuitry mechanisms underlying chronic pain. … Inflammatory pain is an intrinsically dynamic
connectome, … -IL connectivity acts as an inhibitory signal overlying the hypersensitized PL …
connectome, … -IL connectivity acts as an inhibitory signal overlying the hypersensitized PL …
… , oxidative stress and their interplay in neuropathic pain: Focus on specialized pro-resolving mediators and NADPH oxidase inhibitors as potential therapeutic …
L Teixeira-Santos, A Albino-Teixeira, D Pinho - Pharmacological Research, 2020 - Elsevier
… NP arises from a complex interplay of several mechanisms, … and inflammatory signaling that
drives pain sensitization. … reaction occurs early and transiently, astrocytes respond later and …
drives pain sensitization. … reaction occurs early and transiently, astrocytes respond later and …
[HTML][HTML] Inflammation induced sensory nerve growth and pain hypersensitivity requires the N-type calcium channel Cav2. 2
S Pitake, LJ Middleton, I Abdus-Saboor… - Frontiers in …, 2019 - frontiersin.org
… we provide a mechanism for CFA-induced inflammatory pain … alters the intrinsic firing patterns
of sensory neurons during … conotoxin to inhibit Cav2.2 activity during inflammatory states. …
of sensory neurons during … conotoxin to inhibit Cav2.2 activity during inflammatory states. …
Modeling the daily rhythm of human pain processing in the dorsal horn
J Crodelle, SH Piltz, MH Hagenauer… - PLOS Computational …, 2019 - journals.plos.org
… to investigate mechanisms for the daily modulation of pain … It is distinguished from inflammatory
conditions like arthritis in … in pain sensitivity over the 24-hour day mediated by intrinsic …
conditions like arthritis in … in pain sensitivity over the 24-hour day mediated by intrinsic …