[HTML][HTML] The deubiquitinase inhibitor b-AP15 and its effect on phenotype and function of monocyte-derived dendritic cells

M Schmidt, V Altdörfer, S Schnitte, AR Fuchs, KN Kropp… - Neoplasia, 2019 - Elsevier
… in DCs encountering differential proteasome inhibition displayed no … deubiquitinase inhibitor
b-AP15 in contrast to bortezomib. … that the proteasome inhibitor bortezomib influences DC …

Nuclear factor-κB signaling inhibitors revert multidrug-resistance in breast cancer cells

SM Abdin, MF Tolba, DM Zaher, HA Omar - Chemico-Biological Interactions, 2021 - Elsevier
… -κB inhibitor, pentoxifylline (PTX), or the proteasome inhibitor, bortezomib (BTZ), can re-sensitize
breast cancer cells to … The differential basal NF-κB activity in MCF-7 and MDA-MB-231 …

Antitumorigenic action of nelfinavir: Effects on multiple myeloma and hematologic malignancies

A Allegra, V Innao, AG Allegra… - Oncology …, 2020 - spandidos-publications.com
breast cancer cells when compared to HER2-negative cells. In … In a different study, the
proteasome inhibitor bortezomib and … Similarly, no differential action on DOX pharmacokinetics …

Omega-3 fatty acids DHA and EPA reduce bortezomib resistance in multiple myeloma cells by promoting glutathione degradation

J Chen, EA Zaal, CR Berkers, R Ruijtenbeek… - Cells, 2021 - mdpi.com
… While treatment with the proteasome inhibitor bortezomib substantially … FLII has been
recently reported to promote breast cancer … RNA-seq differential gene expression analysis was …

Proteasome inhibitors in medullary thyroid carcinoma: time to restart with clinical trials?

G Fanciulli, R Modica, A La Salvia… - Frontiers in …, 2023 - frontiersin.org
cancer eligible for the phase 2 study (differentiated thyroid … The bortezomib-induced
enhancement of doxorubicin effect … a suppressive effect on bortezomib-induced cytotoxic effect

Lercanidipine Synergistically Enhances Bortezomib Cytotoxicity in Cancer Cells via Enhanced Endoplasmic Reticulum Stress and Mitochondrial Ca2+ Overload

AR Lee, MJ Seo, J Kim, DM Lee, IY Kim… - … journal of molecular …, 2019 - mdpi.com
… and Btz synergistically kill breast cancer cells by inducing … the resistance of cancer cells to
proteasome inhibitors (PIs), we … and Ca 2+ modulation may contribute to the differential effect

… of the unfolded protein response, modulation of protein synthesis, DNA damage, lysosomal impairment, and potentiation of toxicity caused by proteasome inhibition

MR Subeha, AA Goyeneche, P Bustamante, MA Lisio… - bioRxiv, 2021 - biorxiv.org
proteasome inhibitor bortezomib. Overall, our in vitro study demonstrates that NFV can
therapeutically target HGSOC cells of differentialinhibition of HER2-positive breast cancer cells

Mitochondrial dysfunction generates aggregates that resist lysosomal degradation in human breast cancer cells

TG Biel, B Aryal, MH Gerber, JG Trevino… - Cell death & …, 2020 - nature.com
breast cell lines (three cancerous, and one non-cancerous) exposed to MitoQ and MitoApo.
Similar to previous reports 21,22,23 , Bortezomib, a proteasome inhibitor, … by the differential

Proteasome Inhibitors as Sensitizing Agents for Cancer Chemotherapy

Y Liu, WJ Huang, MT Lin, JJ Li, JY Zhang - … Inhibitors as Sensitizing Agents …, 2019 - Elsevier
… example, bortezomib results in neurotoxicity in differentiated … of bortezomib has shown
that proteasome inhibitors are … In breast cancer cells, treatment with paclitaxel and MG132 …

Proteasome inhibition sensitizes liposarcoma to MDM2 inhibition with Nutlin-3 by activating the ATF4/CHOP stress response pathway

MP Ludwig, MD Galbraith, NP Eduthan, AA Hill… - Cancer Research, 2023 - AACR
Differential gene expression was evaluated using DESeq2 (version 1.28.1, RRID:… a panel
of proteasome inhibitors approved by the FDA for blood cancer therapy: bortezomib, ixazomib, …